The following research projects were approved by Susan G. Komen's national Board of Directors for funding, and will be funded once the Grant Agreements between Komen and the Grantee institution(s) are fully-executed. There are 7 types (mechanisms) of grants: Career Catalyst Research (CCR), Graduate Training in Disparities Research (GTDR), Postdoctoral Fellowships (PDF), Komen Scholars Grants (KS), Scientific Advisory Board Grants (SAB), Opportunity Grants (OG), and Sponsored Programs and Partnerships (SPP). For more information on the scientific programs and partnerships that are supported by the Komen Research Program, see here.
Select a column title to sort this information. Select a Project Title for detailed grant information. |
Project Title | Investigators | Organization | State/ Country | Affiliate | Mechanism |
---|---|---|---|---|---|
Identification of drivers and therapeutic targets in brain metastases |
Priscilla Brastianos, M.D. |
Massachusetts General Hospital |
MA |
Massachusetts Affiliate |
CCR Basic/Translational |
Therapeutic exploitation of IRE1a/XBP1 axis of unfolded protein response in TNBC |
Xi Chen Ph.D. |
Baylor College of Medicine |
TX |
Houston Affiliate |
CCR Basic/Translational |
Replication fork damage and breast cancer predisposition |
Alberto Ciccia, Ph.D. |
Columbia University |
NY |
Greater New York City Affiliate |
CCR Basic/Translational |
The role of adipose tissue in obesity-associated breast cancer progression |
Paul Cohen, M.D., Ph.D. |
Rockefeller University |
NY |
Greater New York City Affiliate |
CCR Basic/Translational |
Early stage brain metastasis initiation and colonization from breast cancer |
Bisrat Debeb, Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
CCR Basic/Translational |
Identifying drivers of genomic instability in triple negative breast cancer |
Gaorav Gupta, M.D., Ph.D. |
University of North Carolina at Chapel Hill |
NC |
North Carolina Triangle to the Coast Affiliate |
CCR Basic/Translational |
Novel pro-inflammatory progesterone receptor/STAT1 gene programs in breast cancer |
Christy Hagan, Ph.D. |
University of Kansas Medical Center Research Institute |
KS |
Greater Kansas City Affiliate |
CCR Basic/Translational |
Therapeutic relevance of genetic subtypes within basal-like breast cancer |
Katherine Hoadley, Ph.D. |
University of North Carolina at Chapel Hill |
NC |
North Carolina Triangle to the Coast Affiliate |
CCR Basic/Translational |
PIM kinase as a novel therapeutic target for triple-negative breast cancer |
Dan Horiuchi, Ph.D. |
Northwestern University - Chicago Campus |
IL |
Chicagoland Area Affiliate |
CCR Basic/Translational |
New B-catenin/Tcf inhibitors for the treatment of triple negative breast cancer |
Haitao Ji, Ph.D. |
H. Lee Moffitt Cancer Center and Research Institute |
FL |
Florida Suncoast Affiliate |
CCR Basic/Translational |
Kinome analysis to rationalize targeting HER2 and DDR1 breast cancer mutations |
Shyam Kavuri, Ph.D. |
Baylor College of Medicine |
TX |
Houston Affiliate |
CCR Basic/Translational |
Understanding breast cancer dormancy and reactivation to prevent recurrence |
April Kloxin, Ph.D. |
University of Delaware |
DE |
Philadelphia Affiliate |
CCR Basic/Translational |
Epigenetic regulation of hypoxia-inducible factor 1 activity in breast cancer |
Weibo Luo, Ph.D. |
UT Southwestern Medical Center |
TX |
Dallas County Affiliate |
CCR Basic/Translational |
Targeting Axl in ductal carcinoma in situ |
Heather Machado, Ph.D. |
Tulane University Health Sciences Center |
LA |
New Orleans Affiliate |
CCR Basic/Translational |
Development of anti-HER2 & alpha combination therapy for metastatic breast cancer |
Jessie Nedrow, Ph.D. |
Johns Hopkins University-School of Medicine |
MD |
Maryland Affiliate |
CCR Basic/Translational |
In vivo functional genomics to dissect oncogenic signaling in breast cancer |
Daniel Schramek, Ph.D. |
Sinai Health System (Mount Sinai Hospital) |
Canada |
N/A |
CCR Basic/Translational |
Exploring the influence of lifetime estrogen exposure on breast epigenetic aging |
Mary Sehl, M.D., Ph.D. |
University of California, Los Angeles |
CA |
Los Angeles County Affiliate |
CCR Basic/Translational |
Targeting breast cancer using adoptive cell transfer incorporating vaccination |
Claire Slaney, Ph.D. |
University of Melbourne |
Australia |
N/A |
CCR Basic/Translational |
A novel strategy for anti-mitotic therapy in breast cancer |
Jason Stumpff, Ph.D. |
University of Vermont and State Agricultural College |
VT |
Vermont-New Hampshire Affiliate |
CCR Basic/Translational |
Dnmt2-mediated epigenetic regulation of FZD7 in breast tumor initiation |
Mei Zhang, Ph.D. |
University of Pittsburgh |
PA |
Pittsburgh Affiliate |
CCR Basic/Translational |
Utilizing cell cycle inhibitors to enhance chemotherapy effects in breast cancer |
Amy Clark, M.D. |
University of Pennsylvania |
PA |
Philadelphia Affiliate |
CCR Clinical |
Ipilimumab, Nivolumab and cryoablation in women with resectable breast cancer |
Heather McArthur, M.D. |
Memorial Sloan-Kettering Cancer Center |
NY |
Greater New York City Affiliate |
CCR Clinical |
Imaging and biologic characterization of the sigma-two receptor in breast cancer |
Elizabeth McDonald, M.D., Ph.D. |
University of Pennsylvania |
PA |
Philadelphia Affiliate |
CCR Clinical |
The prone crawl position to reduce toxicity in breast cancer radiotherapy |
Liv Veldeman, Ph.D. |
Ghent University |
Belgium |
N/A |
CCR Clinical |
Reduction of symptom impacts on sedentarism and associated biomarkers |
Rachel Walker, Ph.D. |
University of Massachusetts Amherst |
MA |
Massachusetts Affiliate |
CCR Clinical |
The University of Chicago Graduate Training Program in Breast Cancer Disparities |
Mary Dolan, Ph.D. |
University of Chicago |
IL |
Chicagoland Area Affiliate |
Graduate Training and Disparities |
Graduate Training Program to Advance Breast Cancer Care in Ethiopia |
Eva Kantelhardt, M.D. |
Martin-Luther-University Halle Medical Faculty |
Germany |
Susan G. Komen Deutschland e.V. |
Graduate Training and Disparities |
Breast Cancer Mortality Disparities: Integrating Biology and Access |
Melissa Troester, Ph.D. |
University of North Carolina at Chapel Hill (Chapel Hill, NC) |
NC |
North Carolina Triangle to the Coast Affiliate |
Graduate Training and Disparities |
Training Minorities in Research to Reduce Breast Cancer Disparities |
Kevin Williams, Ph.D. |
North Carolina Central University |
NC |
North Carolina Triangle to the Coast Affiliate |
Graduate Training and Disparities |
Regulation of breast cancer dormancy by the microenvironment |
Jean Albrengues, Ph.D. |
Cold Spring Harbor Laboratory |
NY |
Greater New York City Affiliate |
PDF Basic and Translational |
Elucidating the mechanisms by which a cholesterol metabolite promotes metastasis |
Amy Baek, Ph.D. |
The Board of Trustees of the University of Illinois at Urbana-Champaign |
IL |
Memorial Affiliate |
PDF Basic and Translational |
Development of PI3Kß-based combination therapies in PTEN-deficient breast cancer |
Johann Bergholz, Ph.D. |
Dana-Farber Cancer Institute |
MA |
Massachusetts Affiliate |
PDF Basic and Translational |
Role of lymphatic vessels in breast cancer metastasis and resistance to therapy |
Mirela Berisa, Ph.D. |
Icahn School of Medicine at Mount Sinai |
NY |
Greater New York City Affiliate |
PDF Basic and Translational |
ATR-dependent regulation of PALB2 in breast cancers |
Remi Buisson, Ph.D. |
Massachusetts General Hospital |
MA |
Massachusetts Affiliate |
PDF Basic and Translational |
Assessing the role of lncRNAs in metastatic breast cancer |
Sarah Diermeier, Ph.D. |
Cold Spring Harbor Laboratory |
NY |
Greater New York City Affiliate |
PDF Basic and Translational |
Tracing mechanisms of cellular heterogeneity and drug resistance in breast cancer |
Gabriel Eades, Ph.D. |
University of California, San Francisco |
CA |
San Francisco Bay Area Affiliate |
PDF Basic and Translational |
The macrophage-stimulating protein/Ron pathway in breast cancer bone metastasis |
Jamie Fornetti, Ph.D. |
University of Utah |
UT |
Utah Affiliate |
PDF Basic and Translational |
Elucidating the niche regulating disseminated breast tumor cell dormancy in liver |
Candice Grzelak, Ph.D. |
Fred Hutchinson Cancer Research Center |
WA |
Puget Sound Affiliate |
PDF Basic and Translational |
Defining high-risk precursor signaling to advance breast cancer prevention |
Mihriban Karaayvaz, Ph.D. |
Massachusetts General Hospital |
MA |
Massachusetts Affiliate |
PDF Basic and Translational |
Functions of BRCA2 and RAD51 paralogs in suppression of breast cancer tumors |
Artem Lada, Ph.D. |
University of California at Davis |
CA |
Sacramento Valley Affiliate |
PDF Basic and Translational |
Conformation-specific targeting of ß1 integrins for breast cancer treatment |
Jing Li, Ph.D. |
Children's Hospital Boston |
MA |
Massachusetts Affiliate |
PDF Basic and Translational |
Impact of DNA break repair and chromosomal rearrangements on breast cancer |
Yana Miteva, Ph.D. |
Columbia University Medical Center |
NY |
Greater New York City Affiliate |
PDF Basic and Translational |
Estrogens, inflammation and the aggressive behavior of breast cancer in obesity |
Manuel Picon-Ruiz, Ph.D. |
Miller School of Medicine of the University of Miami |
FL |
Miami/Ft. Lauderdale Affiliate |
PDF Basic and Translational |
Effect of neomorphic mutant p53 activity on TNBC sensitivity to Chk1 inhibition |
Abena Redwood, Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
PDF Basic and Translational |
Chromatin regulatory subunits as mediators of tumor progression and resistance |
Jose Seoane, Ph.D. |
Stanford University |
CA |
San Francisco Bay Area Affiliate |
PDF Basic and Translational |
Reprogramming the tumor microenvironment to prevent breast cancer recurrence |
Sema Sevimli, Ph.D. |
Vanderbilt University |
TN |
Greater Nashville Affiliate |
PDF Basic and Translational |
Bivalent antagonists for overcoming endocrine-resistant breast cancer |
Abhishek Sharma, Ph.D. |
University of Illinois at Urbana-Champaign |
IL |
Memorial Affiliate |
PDF Basic and Translational |
Subtype-specific causes of resistance to HER2 therapy in patients and xenografts |
Maki Tanioka, M.D., Ph.D. |
University of North Carolina at Chapel Hill |
NC |
North Carolina Triangle to the Coast Affiliate |
PDF Basic and Translational |
Circulating tumor cell heterogeneity during breast cancer metastatic progression |
Nicole Vincent Jordan, Ph.D. |
Massachusetts General Hospital |
MA |
Massachusetts Affiliate |
PDF Basic and Translational |
Development of a decision aid on BRCA genetic testing for Orthodox Jewish women |
Meghna Trivedi, M.D. |
Columbia University Medical Center |
NY |
Greater New York City Affiliate |
PDF Clinical |
Disseminating and Implementing BHGI Guidelines in Latin America and the Caribbean |
Benjamin Anderson, M.D. |
Fred Hutchinson Cancer Research Center |
WA |
Puget Sound Affiliate |
Komen Scholars |
Profiling Breast Cancer After Pre-Surgical Therapy: A Platform for Discovery of Mechanisms of Drug Resistance |
Carlos L. Arteaga, M.D. |
Vanderbilt University Medical Center |
TN |
Greater Nashville Affiliate |
Scientific Advisory Board |
Establishing Novel Therapeutic Approaches For Breast Cancer |
Alan Ashworth, Ph.D. |
University of California, San Francisco |
CA |
San Francisco Bay Area Affiliate |
Komen Scholars |
Molecular Characterization of Interval Breast Cancers |
Abenaa M. Brewster, M.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
Komen Scholars |
(SAB) Elucidating ER Transcriptional Network Associated With Endocrine Resistance |
Myles Brown, M.D. |
Dana-Farber Cancer Institute |
MA |
Massachusetts Affiliate |
Scientific Advisory Board |
Targeting the MELK protein for the treatment of triple-negative breast cancer |
Powel Brown, M.D./Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
Scientific Advisory Board |
Translating Biology Into Therapeutic Advances |
Lisa Carey, M.D. |
University of North Carolina at Chapel Hill |
NC |
North Carolina Triangle to the Coast Affiliate |
Komen Scholars |
Hormonal cross-talk and the role of mutations in breast cancer |
Jason Carroll, Ph.D. |
The Chancellor, Masters and Scholars of the University of Cambridge |
United Kingdom |
N/A |
Komen Scholars |
Limiting the inflammation of obesity to prevent breast cancer |
Mary L. "Nora" Disis, M.D. |
University of Washington |
WA |
Puget Sound Affiliate |
Komen Scholars |
Prospective Registry of Multiplex Genetic Testing for Cancer Susceptibility (PROMPT) |
Susan Domchek, M.D. |
The Trustees of the University of Pennsylvania |
PA |
Philadelphia Affiliate |
Komen Scholars |
Mechanisms of Resistance to Treatment of Her2 Positive Metastatic Breast Cancer |
Joe Gray, Ph.D. |
Oregon Health and Science University |
OR |
Oregon and SW Washington Affiliate |
Komen Scholars |
Comorbidity, toxicity and breast cancer survival among women on and off clinical trials |
Dawn Hershman, M.D. |
The Trustees of Columbia University in the City of New York |
NY |
Greater New York City Affiliate |
Komen Scholars |
An E-selectin-mediated endothelial niche in bone metastasis of breast cancer |
Yibin Kang, Ph.D. |
Princeton University |
NJ |
Central and South Jersey Affiliate |
Komen Scholars |
Defining the Key Principles of a Breast Cancer Preventive Vaccine |
Keith Knutson, Ph.D. |
Mayo Clinic Jacksonville |
FL |
North Florida Affiliate |
Komen Scholars |
Elucidating Novel Mechanisms of Resistance to HER2-directed Therapy |
Ian Krop, M.D./Ph.D. |
Dana-Farber Cancer Institute |
MA |
Massachusetts Affiliate |
Komen Scholars |
Genomics of Breast Cancer Metastasis to Brain |
Adrian Lee, Ph.D. |
University of Pittsburgh |
PA |
Pittsburgh Affiliate |
Komen Scholars |
Clinical decision support for precision breast cancer treatment |
Mia Levy, M.D. |
Vanderbilt University Medical Center |
TN |
Greater Nashville Affiliate |
Komen Scholars |
Breast Cancer Weight Loss (BWEL) Study |
Jennifer Ligibel, M.D. |
Dana-Farber Cancer Institute |
MA |
Massachusetts Affiliate |
Komen Scholars |
Molecular Imaging of Breast Cancer Metabolism to Predict In Vivo Cancer Behavior |
David Mankoff, M.D./Ph.D. |
The Trustees of the University of Pennsylvania |
PA |
Philadelphia Affiliate |
Komen Scholars |
Impact of LOFT training on muscular recovery after breast cancer treatment |
Kathy Miller, M.D. |
Indiana University |
IN |
Central Indiana Affiliate |
Komen Scholars |
Combinatorial Adaptive Resistance Therapy In Breast Cancer |
Gordon Mills, M.D./Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
Komen Scholars |
Triple Negative Breast Cancer in Women with African Ancestry |
Lisa Newman, M.D. |
Henry Ford Health System |
MI |
Detroit Race for the Cure |
Komen Scholars |
Identification of unique drivers of ILC progression |
Steffi Oesterreich, Ph.D. |
University of Pittsburgh |
PA |
Pittsburgh Affiliate |
Komen Scholars |
Biological Consequences Of Novel PTEN Pathway Signaling Defects In Breast Cancer |
Ramon Parsons, M.D./Ph.D. |
Icahn School of Medicine at Mount Sinai |
NY |
Greater New York City Affiliate |
Komen Scholars |
2nd Opinions and the Treatment Gradient Among African Americans with Breast Cancer |
Rena Pasick, Dr.P.H. |
University of California, San Francisco |
CA |
San Francisco Bay Area Affiliate |
Komen Scholars |
Identification of the Genetic Drivers of HER2-Enriched Subtype Breast Cancers |
Charles Perou, Ph.D. |
University of North Carolina at Chapel Hill |
NC |
North Carolina Triangle to the Coast Affiliate |
Komen Scholars |
Mammary epithelial progenitors as targets for breast cancer prevention |
Kornelia Polyak, M.D./Ph.D. |
Dana-Farber Cancer Institute |
MA |
Massachusetts Affiliate |
Komen Scholars |
Immunological characterization of primary metastatic breast cancer |
Lajos Pusztai, Ph.D. |
Yale University |
CT |
Southern New England Affiliate |
Komen Scholars |
Improving Adherence to Endocrine Hormonal Therapy among Breast Cancer Patients |
Amelie Ramirez, Dr.P.H. |
University of Texas Health Science Center at San Antonio |
TX |
San Antonio Affiliate |
Scientific Advisory Board |
MBI vs. ultrasound after negative screening tomosynthesis in dense breasts |
Deborah Rhodes, M.D. |
Mayo Clinic |
MN |
Minnesota Affiliate |
Komen Scholars |
Genomic Predictors of Chemotherapy-Induced Toxicity |
Bryan Schneider, M.D. |
Indiana University Melvin And Bren Simon Cancer Center |
IN |
Central Indiana Affiliate |
Komen Scholars |
Measuring Circulating Tumor Cells in vivo for Breast Cancer Metastasis Detection |
George Sledge, M.D. |
Stanford University |
CA |
San Francisco Bay Area Affiliate |
Scientific Advisory Board |
Molecular Characterization of Invasive Lobular Breast Cancer |
Christos Sotiriou, M.D./Ph.D. |
Jules Bordet Institute |
N/A |
N/A |
Komen Scholars |
Regulation Of Metastasis By Mitochondrial DNA |
Danny Welch, Ph.D. |
University of Kansas Medical Center Research Institute, Inc. |
KS |
Greater Kansas City Affiliate |
Komen Scholars |
A personalized vaccine immunotherapy strategy to prevent breast cancer metastasis |
Alana Welm, Ph.D. |
University of Utah |
UT |
Utah Affiliate |
Komen Scholars |
Improving Treatment Approaches For Women With HER2+ Metastatic Breast Cancer |
Eric Winer, M.D. |
Dana-Farber Cancer Institute |
MA |
Massachusetts Affiliate |
Scientific Advisory Board |
Johns Hopkins Breast Cancer Program Longitudinal Repository |
Antonio Wolff, M.D. |
Johns Hopkins Univ. School of Medicine |
M.D. |
Maryland Affiliate |
Komen Scholars |
Identifying Translational Regulated Genes Activated By Insulin-like Growth Factor Signaling |
Douglas Yee, M.D. |
Regents of University of Minnesota |
MN |
Minnesota Affiliate |
Komen Scholars |
New drugs for metastatic breast cancer |
Suranganie Dharmawardhane, Ph.D. |
University of Puerto Rico, Medical Sciences Campus |
Puerto Rico |
Puerto Rico Affiliate |
Opportunity Grants |
Extending the Global Surveillance of Breast Cancer Survival (CONCORD-3) |
Michel Coleman, Ph.D. |
London School of Hygiene & Tropical Medicine |
United Kingdom |
N/A |
Opportunity Grants |
Tumor and Germline Genomic Analysis in Young Patients with Metastatic Breast Cancer |
Nikhil Wagle, Ph.D. |
Broad Institute |
MA |
Massachusetts Affiliate |
Opportunity Grants |
Expanding the Role of Promotores/Community Health Workers in Promoting Prevention and Dispelling Myths |
Venus Gines, M.A. |
Dia de La Mujer Latina |
TX |
Houston Affiliate |
Sponsored Partnerships and Programs |
Triple Negative Breast Cancer Workshop at ANMA’s 2015 Annual Conference |
Velva Clark, R.N., B.S. |
Auxiliary of the National Medical Association |
MI |
Detroit Race for the Cure |
Sponsored Partnerships and Programs |
2015 Metastatic Breast Cancer Network Annual Meeting October 16-17 2015 in Boston MA |
Shirley Mertz, J.D. |
Metastatic Breast Cancer Network |
IL |
Chicagoland Area Affiliate |
Sponsored Partnerships and Programs |
Living Beyond Breast Cancer FY16 Programming |
Jean Sachs, M.S.S., M.L.S.P. |
Living Beyond Breast Cancer |
PA |
Philadelphia Affiliate |
Sponsored Partnerships and Programs |
Friends of Cancer Research/Brookings Conference on Clinical Cancer Research to be held on November 17, 2015 |
Jeff Allen, Ph.D. |
Friends of Cancer Research |
DC |
N/A |
Sponsored Partnerships and Programs |
Conference Sponsorship for AACR FY16 Programming |
Michael Stewart |
American Association for Cancer Research |
PA |
Philadelphia Affiliate |
Sponsored Partnerships and Programs |
Training to Improve Cell Authentication Practice Among Breast Cancer Researchers |
Leonard Freedman, Ph.D. |
Global Biological Standards Institute |
DC |
N/A |
Sponsored Partnerships and Programs |
2016 Conference Series: National Summit & Regional Symposia |
Jennifer Merschdorf |
Young Survival Coalition |
NY |
Greater New York City Affiliate |
Sponsored Partnerships and Programs |
Susan G. Komen® Symposium: Selective Management of DCIS and the Susan G. Komen® Breast Cancer Research Award |
Eileen Widmer |
The Society of Surgical Oncology |
IL |
Chicagoland Area Affiliate |
Sponsored Partnerships and Programs |
2016 Accelerating Anticancer Agent Development and Validation Workshop |
H. Kim Lyerly, M.D. |
Duke University |
NC |
North Carolina Triangle to the Coast Affiliate |
Sponsored Partnerships and Programs |
AACR Annual Meeting 2016 |
Mitch Stoller |
American Association for Cancer Research |
PA |
Philadelphia Affiliate |
Sponsored Partnerships and Programs |
1st International Invasive Lobular Cancer (ILC) Symposium |
Steffi Oesterreich, Ph.D. |
University of Pittsburgh Cancer Institute |
PA |
Pittsburgh Affiliate |
Sponsored Partnerships and Programs |
IABCR/ Early Detection of Lethal Breast Cancers |
Heidi Feiler, Ph.D. |
Oregon Health & Science University |
OR |
Oregon and SW Washington Affiliate |
Sponsored Partnerships and Programs |
Komen Tissue Bank Think Tank |
Anna Maria Stornolio, M.D. |
Komen Tissue Bank |
IN |
Central Indiana Affiliate |
Sponsored Partnerships and Programs |
24th Biennial Congress of the European Association for Cancer Research (EACR24) |
Rachel Warden |
European Association for Cancer Research (EACR) |
United Kingdom |
N/A |
Sponsored Partnerships and Programs |
Obesity Week 2016; Obesity and Cancer Section Events |
Wendy Demark-Wahnefried, Ph.D, R.D. |
The Obesity Society |
AL |
North Central Alabama Affiliate |
Sponsored Partnerships and Programs |
Inclusion of Breast Cancer Patients with Bone-only Metastasis in Clinical Trials Consensus Development Meeting (Think Tank) |
Julie Gralow, M.D. |
University of Washington |
WA |
Puget Sound Affiliate |
Sponsored Partnerships and Programs |