The following research projects were approved by Susan G. Komen's national Board of Directors for funding, and will be funded once the Grant Agreements between Komen and the Grantee institution(s) are fully-executed. There are 7 types (mechanisms) of grants: Career Catalyst Research (CCR), Graduate Training in Disparities Research (GTDR), Postdoctoral Fellowships (PDF), Komen Scholars Grants (KS), Scientific Advisory Board Grants (SAB), Opportunity Grants (OG), and Sponsored Programs and Partnerships (SPP). For more information on the scientific programs and partnerships that are supported by the Komen Research Program, see here.

Select a column title to sort this information.
Select a Project Title for detailed grant information.
Download Printable Version

Type to Search:
Project Title Investigators Organization State/ Country Affiliate Mechanism

Identification of drivers and therapeutic targets in brain metastases

Priscilla Brastianos, M.D.

Massachusetts General Hospital

MA

Massachusetts Affiliate

CCR Basic/Translational

Therapeutic exploitation of IRE1a/XBP1 axis of unfolded protein response in TNBC

Xi Chen Ph.D.

Baylor College of Medicine

TX

Houston Affiliate

CCR Basic/Translational

Replication fork damage and breast cancer predisposition

Alberto Ciccia, Ph.D.

Columbia University

NY

Greater New York City Affiliate

CCR Basic/Translational

The role of adipose tissue in obesity-associated breast cancer progression

Paul Cohen, M.D., Ph.D.

Rockefeller University

NY

Greater New York City Affiliate

CCR Basic/Translational

Early stage brain metastasis initiation and colonization from breast cancer

Bisrat Debeb, Ph.D.

University of Texas M.D. Anderson Cancer Center

TX

Houston Affiliate

CCR Basic/Translational

Identifying drivers of genomic instability in triple negative breast cancer

Gaorav Gupta, M.D., Ph.D.

University of North Carolina at Chapel Hill

NC

North Carolina Triangle to the Coast Affiliate

CCR Basic/Translational

Novel pro-inflammatory progesterone receptor/STAT1 gene programs in breast cancer

Christy Hagan, Ph.D.

University of Kansas Medical Center Research Institute

KS

Greater Kansas City Affiliate

CCR Basic/Translational

Therapeutic relevance of genetic subtypes within basal-like breast cancer

Katherine Hoadley, Ph.D.

University of North Carolina at Chapel Hill

NC

North Carolina Triangle to the Coast Affiliate

CCR Basic/Translational

PIM kinase as a novel therapeutic target for triple-negative breast cancer

Dan Horiuchi, Ph.D.

Northwestern University - Chicago Campus

IL

Chicagoland Area Affiliate

CCR Basic/Translational

New B-catenin/Tcf inhibitors for the treatment of triple negative breast cancer

Haitao Ji, Ph.D.

H. Lee Moffitt Cancer Center and Research Institute

FL

Florida Suncoast Affiliate

CCR Basic/Translational

Kinome analysis to rationalize targeting HER2 and DDR1 breast cancer mutations

Shyam Kavuri, Ph.D.

Baylor College of Medicine

TX

Houston Affiliate

CCR Basic/Translational

Understanding breast cancer dormancy and reactivation to prevent recurrence

April Kloxin, Ph.D.

University of Delaware

DE

Philadelphia Affiliate

CCR Basic/Translational

Epigenetic regulation of hypoxia-inducible factor 1 activity in breast cancer

Weibo Luo, Ph.D.

UT Southwestern Medical Center

TX

Dallas County Affiliate

CCR Basic/Translational

Targeting Axl in ductal carcinoma in situ

Heather Machado, Ph.D.

Tulane University Health Sciences Center

LA

New Orleans Affiliate

CCR Basic/Translational

Development of anti-HER2 & alpha combination therapy for metastatic breast cancer

Jessie Nedrow, Ph.D.

Johns Hopkins University-School of Medicine

MD

Maryland Affiliate

CCR Basic/Translational

In vivo functional genomics to dissect oncogenic signaling in breast cancer

Daniel Schramek, Ph.D.

Sinai Health System (Mount Sinai Hospital)

Canada

N/A

CCR Basic/Translational

Exploring the influence of lifetime estrogen exposure on breast epigenetic aging

Mary Sehl, M.D., Ph.D.

University of California, Los Angeles

CA

Los Angeles County Affiliate

CCR Basic/Translational

Targeting breast cancer using adoptive cell transfer incorporating vaccination

Claire Slaney, Ph.D.

University of Melbourne

Australia

N/A

CCR Basic/Translational

A novel strategy for anti-mitotic therapy in breast cancer

Jason Stumpff, Ph.D.

University of Vermont and State Agricultural College

VT

Vermont-New Hampshire Affiliate

CCR Basic/Translational

Dnmt2-mediated epigenetic regulation of FZD7 in breast tumor initiation

Mei Zhang, Ph.D.

University of Pittsburgh

PA

Pittsburgh Affiliate

CCR Basic/Translational

Utilizing cell cycle inhibitors to enhance chemotherapy effects in breast cancer

Amy Clark, M.D.

University of Pennsylvania

PA

Philadelphia Affiliate

CCR Clinical

Ipilimumab, Nivolumab and cryoablation in women with resectable breast cancer

Heather McArthur, M.D.

Memorial Sloan-Kettering Cancer Center

NY

Greater New York City Affiliate

CCR Clinical

Imaging and biologic characterization of the sigma-two receptor in breast cancer

Elizabeth McDonald, M.D., Ph.D.

University of Pennsylvania

PA

Philadelphia Affiliate

CCR Clinical

The prone crawl position to reduce toxicity in breast cancer radiotherapy

Liv Veldeman, Ph.D.

Ghent University

Belgium

N/A

CCR Clinical

Reduction of symptom impacts on sedentarism and associated biomarkers

Rachel Walker, Ph.D.

University of Massachusetts Amherst

MA

Massachusetts Affiliate

CCR Clinical

The University of Chicago Graduate Training Program in Breast Cancer Disparities

Mary Dolan, Ph.D.

University of Chicago

IL

Chicagoland Area Affiliate

Graduate Training and Disparities

Graduate Training Program to Advance Breast Cancer Care in Ethiopia

Eva Kantelhardt, M.D.

Martin-Luther-University Halle Medical Faculty

Germany

Susan G. Komen Deutschland e.V.

Graduate Training and Disparities

Breast Cancer Mortality Disparities: Integrating Biology and Access

Melissa Troester, Ph.D.

University of North Carolina at Chapel Hill (Chapel Hill, NC)

NC

North Carolina Triangle to the Coast Affiliate

Graduate Training and Disparities

Training Minorities in Research to Reduce Breast Cancer Disparities

Kevin Williams, Ph.D.

North Carolina Central University

NC

North Carolina Triangle to the Coast Affiliate

Graduate Training and Disparities

Regulation of breast cancer dormancy by the microenvironment

Jean Albrengues, Ph.D.

Cold Spring Harbor Laboratory

NY

Greater New York City Affiliate

PDF Basic and Translational

Elucidating the mechanisms by which a cholesterol metabolite promotes metastasis

Amy Baek, Ph.D.

The Board of Trustees of the University of Illinois at Urbana-Champaign

IL

Memorial Affiliate

PDF Basic and Translational

Development of PI3Kß-based combination therapies in PTEN-deficient breast cancer

Johann Bergholz, Ph.D.

Dana-Farber Cancer Institute

MA

Massachusetts Affiliate

PDF Basic and Translational

Role of lymphatic vessels in breast cancer metastasis and resistance to therapy

Mirela Berisa, Ph.D.

Icahn School of Medicine at Mount Sinai

NY

Greater New York City Affiliate

PDF Basic and Translational

ATR-dependent regulation of PALB2 in breast cancers

Remi Buisson, Ph.D.

Massachusetts General Hospital

MA

Massachusetts Affiliate

PDF Basic and Translational

Assessing the role of lncRNAs in metastatic breast cancer

Sarah Diermeier, Ph.D.

Cold Spring Harbor Laboratory

NY

Greater New York City Affiliate

PDF Basic and Translational

Tracing mechanisms of cellular heterogeneity and drug resistance in breast cancer

Gabriel Eades, Ph.D.

University of California, San Francisco

CA

San Francisco Bay Area Affiliate

PDF Basic and Translational

The macrophage-stimulating protein/Ron pathway in breast cancer bone metastasis

Jamie Fornetti, Ph.D.

University of Utah

UT

Utah Affiliate

PDF Basic and Translational

Elucidating the niche regulating disseminated breast tumor cell dormancy in liver

Candice Grzelak, Ph.D.

Fred Hutchinson Cancer Research Center

WA

Puget Sound Affiliate

PDF Basic and Translational

Defining high-risk precursor signaling to advance breast cancer prevention

Mihriban Karaayvaz, Ph.D.

Massachusetts General Hospital

MA

Massachusetts Affiliate

PDF Basic and Translational

Functions of BRCA2 and RAD51 paralogs in suppression of breast cancer tumors

Artem Lada, Ph.D.

University of California at Davis

CA

Sacramento Valley Affiliate

PDF Basic and Translational

Conformation-specific targeting of ß1 integrins for breast cancer treatment

Jing Li, Ph.D.

Children's Hospital Boston

MA

Massachusetts Affiliate

PDF Basic and Translational

Impact of DNA break repair and chromosomal rearrangements on breast cancer

Yana Miteva, Ph.D.

Columbia University Medical Center

NY

Greater New York City Affiliate

PDF Basic and Translational

Estrogens, inflammation and the aggressive behavior of breast cancer in obesity

Manuel Picon-Ruiz, Ph.D.

Miller School of Medicine of the University of Miami

FL

Miami/Ft. Lauderdale Affiliate

PDF Basic and Translational

Effect of neomorphic mutant p53 activity on TNBC sensitivity to Chk1 inhibition

Abena Redwood, Ph.D.

University of Texas M.D. Anderson Cancer Center

TX

Houston Affiliate

PDF Basic and Translational

Chromatin regulatory subunits as mediators of tumor progression and resistance

Jose Seoane, Ph.D.

Stanford University

CA

San Francisco Bay Area Affiliate

PDF Basic and Translational

Reprogramming the tumor microenvironment to prevent breast cancer recurrence

Sema Sevimli, Ph.D.

Vanderbilt University

TN

Greater Nashville Affiliate

PDF Basic and Translational

Bivalent antagonists for overcoming endocrine-resistant breast cancer

Abhishek Sharma, Ph.D.

University of Illinois at Urbana-Champaign

IL

Memorial Affiliate

PDF Basic and Translational

Subtype-specific causes of resistance to HER2 therapy in patients and xenografts

Maki Tanioka, M.D., Ph.D.

University of North Carolina at Chapel Hill

NC

North Carolina Triangle to the Coast Affiliate

PDF Basic and Translational

Circulating tumor cell heterogeneity during breast cancer metastatic progression

Nicole Vincent Jordan, Ph.D.

Massachusetts General Hospital

MA

Massachusetts Affiliate

PDF Basic and Translational

Development of a decision aid on BRCA genetic testing for Orthodox Jewish women

Meghna Trivedi, M.D.

Columbia University Medical Center

NY

Greater New York City Affiliate

PDF Clinical

Disseminating and Implementing BHGI Guidelines in Latin America and the Caribbean

 Benjamin Anderson, M.D.

Fred Hutchinson Cancer Research Center

WA

Puget Sound Affiliate

Komen Scholars

Profiling Breast Cancer After Pre-Surgical Therapy: A Platform for Discovery of Mechanisms of Drug Resistance

 Carlos L. Arteaga, M.D.

Vanderbilt University Medical Center

TN

Greater Nashville Affiliate

Scientific Advisory Board

Establishing Novel Therapeutic Approaches For Breast Cancer

 Alan  Ashworth, Ph.D.

University of California, San Francisco

CA

San Francisco Bay Area Affiliate

Komen Scholars

Molecular Characterization of Interval Breast Cancers

 Abenaa M. Brewster, M.D.

University of Texas M.D. Anderson Cancer Center

TX

Houston Affiliate

Komen Scholars

(SAB) Elucidating ER Transcriptional Network Associated With Endocrine Resistance

 Myles Brown, M.D.

Dana-Farber Cancer Institute

MA

Massachusetts Affiliate

Scientific Advisory Board

Targeting the MELK protein for the treatment of triple-negative breast cancer

 Powel Brown, M.D./Ph.D.

University of Texas M.D. Anderson Cancer Center

TX

Houston Affiliate

Scientific Advisory Board

Translating Biology Into Therapeutic Advances

 Lisa  Carey, M.D.

University of North Carolina at Chapel Hill

NC

North Carolina Triangle to the Coast Affiliate

Komen Scholars

Hormonal cross-talk and the role of mutations in breast cancer

 Jason Carroll, Ph.D.

The Chancellor, Masters and Scholars of the University of Cambridge

United Kingdom

N/A

Komen Scholars

Limiting the inflammation of obesity to prevent breast cancer

 Mary L. "Nora"  Disis, M.D.

University of Washington

WA

Puget Sound Affiliate

Komen Scholars

Prospective Registry of Multiplex Genetic Testing for Cancer Susceptibility (PROMPT)

 Susan  Domchek, M.D.

The Trustees of the University of Pennsylvania

PA

Philadelphia Affiliate

Komen Scholars

Mechanisms of Resistance to Treatment of Her2 Positive Metastatic Breast Cancer

 Joe  Gray, Ph.D.

Oregon Health and Science University

OR

Oregon and SW Washington Affiliate

Komen Scholars

Comorbidity, toxicity and breast cancer survival among women on and off clinical trials

 Dawn Hershman, M.D.

The Trustees of Columbia University in the City of New York

NY

Greater New York City Affiliate

Komen Scholars

An E-selectin-mediated endothelial niche in bone metastasis of breast cancer

 Yibin Kang, Ph.D.

Princeton University

NJ

Central and South Jersey Affiliate

Komen Scholars

Defining the Key Principles of a Breast Cancer Preventive Vaccine

 Keith Knutson, Ph.D.

Mayo Clinic Jacksonville

FL

North Florida Affiliate

Komen Scholars

Elucidating Novel Mechanisms of Resistance to HER2-directed Therapy

 Ian Krop, M.D./Ph.D.

Dana-Farber Cancer Institute

MA

Massachusetts Affiliate

Komen Scholars

Genomics of Breast Cancer Metastasis to Brain

 Adrian Lee, Ph.D.

University of Pittsburgh

PA

Pittsburgh Affiliate

Komen Scholars

Clinical decision support for precision breast cancer treatment

 Mia Levy, M.D.

Vanderbilt University Medical Center

TN

Greater Nashville Affiliate

Komen Scholars

Breast Cancer Weight Loss (BWEL) Study

 Jennifer Ligibel, M.D.

Dana-Farber Cancer Institute

MA

Massachusetts Affiliate

Komen Scholars

Molecular Imaging of Breast Cancer Metabolism to Predict In Vivo Cancer Behavior

 David Mankoff, M.D./Ph.D.

The Trustees of the University of Pennsylvania

PA

Philadelphia Affiliate

Komen Scholars

Impact of LOFT training on muscular recovery after breast cancer treatment

 Kathy Miller, M.D.

Indiana University

IN

Central Indiana Affiliate

Komen Scholars

Combinatorial Adaptive Resistance Therapy In Breast Cancer

 Gordon Mills, M.D./Ph.D.

University of Texas M.D. Anderson Cancer Center

TX

Houston Affiliate

Komen Scholars

Triple Negative Breast Cancer in Women with African Ancestry

 Lisa Newman, M.D.

Henry Ford Health System

MI

Detroit Race for the Cure

Komen Scholars

Identification of unique drivers of ILC progression

 Steffi Oesterreich, Ph.D.

University of Pittsburgh

PA

Pittsburgh Affiliate

Komen Scholars

Biological Consequences Of Novel PTEN Pathway Signaling Defects In Breast Cancer

 Ramon Parsons, M.D./Ph.D.

Icahn School of Medicine at Mount Sinai

NY

Greater New York City Affiliate

Komen Scholars

2nd Opinions and the Treatment Gradient Among African Americans with Breast Cancer

 Rena Pasick, Dr.P.H.

University of California, San Francisco

CA

San Francisco Bay Area Affiliate

Komen Scholars

Identification of the Genetic Drivers of HER2-Enriched Subtype Breast Cancers

 Charles Perou, Ph.D.

University of North Carolina at Chapel Hill

NC

North Carolina Triangle to the Coast Affiliate

Komen Scholars

Mammary epithelial progenitors as targets for breast cancer prevention

 Kornelia Polyak, M.D./Ph.D.

Dana-Farber Cancer Institute

MA

Massachusetts Affiliate

Komen Scholars

Immunological characterization of primary metastatic breast cancer

 Lajos Pusztai, Ph.D.

Yale University

CT

Southern New England Affiliate

Komen Scholars

Improving Adherence to Endocrine Hormonal Therapy among Breast Cancer Patients

 Amelie Ramirez, Dr.P.H.

University of Texas Health Science Center at San Antonio

TX

San Antonio Affiliate

Scientific Advisory Board

MBI vs. ultrasound after negative screening tomosynthesis in dense breasts

 Deborah Rhodes, M.D.

Mayo Clinic

MN

Minnesota Affiliate

Komen Scholars

Genomic Predictors of Chemotherapy-Induced Toxicity

 Bryan  Schneider, M.D.

Indiana University Melvin And Bren Simon Cancer Center

IN

Central Indiana Affiliate

Komen Scholars

Measuring Circulating Tumor Cells in vivo for Breast Cancer Metastasis Detection

 George Sledge, M.D.

Stanford University

CA

San Francisco Bay Area Affiliate

Scientific Advisory Board

Molecular Characterization of Invasive Lobular Breast Cancer

 Christos Sotiriou, M.D./Ph.D.

Jules Bordet Institute

N/A

N/A

Komen Scholars

Regulation Of Metastasis By Mitochondrial DNA

 Danny Welch, Ph.D.

University of Kansas Medical Center Research Institute, Inc.

KS

Greater Kansas City Affiliate

Komen Scholars

A personalized vaccine immunotherapy strategy to prevent breast cancer metastasis

 Alana Welm, Ph.D.

University of Utah

UT

Utah Affiliate

Komen Scholars

Improving Treatment Approaches For Women With HER2+ Metastatic Breast Cancer

 Eric Winer, M.D.

Dana-Farber Cancer Institute

MA

Massachusetts Affiliate

Scientific Advisory Board

Johns Hopkins Breast Cancer Program Longitudinal Repository

 Antonio Wolff, M.D.

Johns Hopkins Univ. School of Medicine

M.D.

Maryland Affiliate

Komen Scholars

Identifying Translational Regulated Genes Activated By Insulin-like Growth Factor Signaling

 Douglas Yee, M.D.

Regents of University of Minnesota

MN

Minnesota Affiliate

Komen Scholars

New drugs for metastatic breast cancer

 Suranganie Dharmawardhane, Ph.D.

University of Puerto Rico, Medical Sciences Campus

Puerto Rico

Puerto Rico Affiliate

Opportunity Grants

Extending the Global Surveillance of Breast Cancer Survival (CONCORD-3)

 Michel Coleman, Ph.D.

London School of Hygiene & Tropical Medicine

United Kingdom

N/A

Opportunity Grants

Tumor and Germline Genomic Analysis in Young Patients with Metastatic Breast Cancer

 Nikhil Wagle, Ph.D.

Broad Institute

MA

Massachusetts Affiliate

Opportunity Grants

Expanding the Role of Promotores/Community Health Workers in Promoting Prevention and Dispelling Myths

 Venus Gines, M.A.

Dia de La Mujer Latina

TX

Houston Affiliate

Sponsored Partnerships and Programs

Triple Negative Breast Cancer Workshop at ANMA’s 2015 Annual Conference

 Velva Clark, R.N., B.S.

Auxiliary of the National Medical Association

MI

Detroit Race for the Cure

Sponsored Partnerships and Programs

2015 Metastatic Breast Cancer Network Annual Meeting October 16-17 2015 in Boston MA

 Shirley Mertz, J.D.

Metastatic Breast Cancer Network

IL

Chicagoland Area Affiliate

Sponsored Partnerships and Programs

Living Beyond Breast Cancer FY16 Programming

 Jean Sachs, M.S.S., M.L.S.P.

Living Beyond Breast Cancer

PA

Philadelphia Affiliate

Sponsored Partnerships and Programs

Friends of Cancer Research/Brookings Conference on Clinical Cancer Research to be held on November 17, 2015

 Jeff Allen, Ph.D.

Friends of Cancer Research

DC

N/A

Sponsored Partnerships and Programs

Conference Sponsorship for AACR FY16 Programming

 Michael Stewart

American Association for Cancer Research

PA

Philadelphia Affiliate

Sponsored Partnerships and Programs

Training to Improve Cell Authentication Practice Among Breast Cancer Researchers

 Leonard Freedman, Ph.D.

Global Biological Standards Institute

DC

N/A

Sponsored Partnerships and Programs

2016 Conference Series: National Summit & Regional Symposia

 Jennifer Merschdorf

Young Survival Coalition

NY

Greater New York City Affiliate

Sponsored Partnerships and Programs

Susan G. Komen® Symposium: Selective Management of DCIS  and the Susan G. Komen® Breast Cancer Research Award

 Eileen Widmer

The Society of Surgical Oncology

IL

Chicagoland Area Affiliate

Sponsored Partnerships and Programs

2016 Accelerating Anticancer Agent Development and Validation Workshop

 H. Kim Lyerly, M.D.

Duke University

NC

North Carolina Triangle to the Coast Affiliate

Sponsored Partnerships and Programs

AACR Annual Meeting 2016

 Mitch Stoller

American Association for Cancer Research

PA

Philadelphia Affiliate

Sponsored Partnerships and Programs

1st International Invasive Lobular Cancer (ILC) Symposium

 Steffi Oesterreich, Ph.D.

University of Pittsburgh Cancer Institute

PA

Pittsburgh Affiliate

Sponsored Partnerships and Programs

IABCR/ Early Detection of Lethal Breast Cancers

 Heidi Feiler, Ph.D.

Oregon Health & Science University

OR

Oregon and SW Washington Affiliate

Sponsored Partnerships and Programs

Komen Tissue Bank Think Tank

 Anna Maria Stornolio, M.D.

Komen Tissue Bank

IN

Central Indiana Affiliate

Sponsored Partnerships and Programs

24th Biennial Congress of the European Association for Cancer Research (EACR24)

 Rachel Warden

European Association for Cancer Research (EACR)

United Kingdom

N/A

Sponsored Partnerships and Programs

Obesity Week 2016; Obesity and Cancer Section Events

 Wendy Demark-Wahnefried, Ph.D, R.D.

The Obesity Society

AL

North Central Alabama Affiliate

Sponsored Partnerships and Programs

Inclusion of Breast Cancer Patients with Bone-only Metastasis in Clinical Trials Consensus Development Meeting (Think Tank)

 Julie Gralow, M.D.

University of Washington

WA

Puget Sound Affiliate

Sponsored Partnerships and Programs