The following research projects were approved by Susan G. Komen's national Board of Directors for funding, and will be funded once the Grant Agreements between Komen and the Grantee institution(s) are fully-executed. There are 9 types (mechanisms) of grants: Career Catalyst Research (CCR), Career Catalyst Research Competitive Renewal (CCR-CR), Graduate Training in Disparities Research (GTDR), Komen Scholars Grants (KS), Opportunity Grants (OG), Postdoctoral Fellowships (PDF), Scientific Advisory Board Grants (SAB), Sponsored Programs and Partnerships (SPP) and Inflammatory Breast Cancer Innovator Grants: Funded in Partnership with the Milburn Foundation and the Inflammatory Breast Cancer Research Foundation (IBC). For more information on the scientific programs and partnerships that are supported by the Komen Research Program, see here.
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Project Title | Investigators | Organization | State/ Country | Affiliate | Mechanism |
---|---|---|---|---|---|
Immune Regulation of TNBC Metastasis |
Swarnali Acharyya, Ph.D. |
Columbia University Medical Center |
NY |
Greater New York City Affiliate |
CCR Basic/Translational |
Enhancing Breast Cancer Treatment Responses by Targeting Genetic Host Factors |
Carmen Bergom, M.D., Ph.D. |
Medical College of Wisconsin |
WI |
Wisconsin Affiliate |
CCR Basic/Translational |
Role of Cancer Stem Cells in Mediating Resistance to DNA Repair Targeting Therapy |
Monika Burness, M.D. |
University of Michigan |
MI |
Michigan Affiliate |
CCR Basic/Translational |
Oncogene Roles of the DNA Damage Transducer RNF8 in Basal-Like Breast Cancer |
Chia-Hsin Chan, Ph.D. |
The Research Foundation for The State University of New York |
NY |
Upstate New York Affiliate |
CCR Basic/Translational |
Defining Carcinoma-Astrocyte Interactions in Breast Cancer Brain Metastasis |
Qing Chen, Ph.D., M.D. |
The Wistar Institute |
PA |
Philadelphia Affiliate |
CCR Basic/Translational |
Co-Targetting Tissue Stiffness to Improve the Efficacy of Breast Cancer Therapies |
Thomas Cox, Ph.D. |
Garvan Institute of Medical Research |
Australia |
N/A |
CCR Basic/Translational |
Identifying Adaptations to Chronic Hypoxia in TNBC Metastasis |
Daniele Gilkes, Ph.D. |
Johns Hopkins University |
MD |
Maryland Affiliate |
CCR Basic/Translational |
Clusters of Enhancers and Associated RNAs in DCIS Progression |
Jason Herschkowitz, Ph.D. |
The Research Foundation for The State University of New York |
NY |
Upstate New York Affiliate |
CCR Basic/Translational |
Targeting Aberrant YAP/TAZ Activation in Metastatic Breast Cancer |
John Lamar, Ph.D. |
Albany Medical College |
NY |
Upstate New York Affiliate |
CCR Basic/Translational |
A Novel Strategy of Immunotherapy by Targeting Glycosylation of PD-L1 |
Seung-Oe Lim, Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
CCR Basic/Translational |
Enhancer Component/Architectural Changes in Breast Cancer Hormone Resistance |
Zhijie Liu, Ph. D. |
University of Texas Health Science Center at San Antonio |
TX |
San Antonio Affiliate |
CCR Basic/Translational |
Overcoming Environmental Therapy Resistance in TNBC |
Andriy Marusyk, Ph.D. |
H. Lee Moffitt Cancer Center & Research Institute |
FL |
Florida Suncoast Affiliate |
CCR Basic/Translational |
Delineating and Exploiting HSF1 Activation in Highly Malignant Breast Cancers |
Marc Mendillo, Ph.D. |
Northwestern University, Chicago |
IL |
Chicago Affiliate |
CCR Basic/Translational |
HDAC11 Promotes Breast Cancer Metastasis via the Lymphatic Route |
Chad Pecot, M.D. |
The University of North Carolina, Chapel Hill |
NC |
North Carolina Triangle to the Coast Affiliate |
CCR Basic/Translational |
Understanding How Commensal Dysbiosis Drives Metastatic Breast Cancer |
Melanie Rutkowski, Ph.D. |
University of Virginia School of Medicine |
VA |
Central Virginia Affiliate |
CCR Basic/Translational |
Characterization of Disseminated Breast Cancer Cells and Relevance to Metastasis |
Maria Sosa, Ph.D. |
Icahn School of Medicine, Mount Sinai |
NY |
Greater New York City Affiliate |
CCR Basic/Translational |
Targeting Genomic Drivers of Chemoresistant TNBC |
Daniel Stover, M.D. |
The Ohio State University |
OH |
Columbus Affiliate |
CCR Basic/Translational |
Growth Factor Signaling in Obesity Associated Breast Cancer |
Elizabeth Wellberg, Ph.D. |
University of Colorado, Denver |
CO |
Colorado Affiliate |
CCR Basic/Translational |
Breast Cancer Screening Through the Combination of Light and Ultrasound |
Jun Xia, Ph.D. |
The Research Foundation for The State University of New York |
NY |
Upstate New York Affiliate |
CCR Basic/Translational |
Early Detection of Breast Cancer Among Women at High Risk for Screening Failure |
Anne Marie McCarthy, Ph.D. |
Massachusetts General Hospital |
MA |
New England Affiliate |
CCR Clinical |
Time to Act - Implementing Strategies for Breast Cancer Control In Africa |
Anne Rositch, Ph.D. |
Johns Hopkins University |
MD |
Maryland Affiliate |
CCR Clinical |
A New Paradigm - Using PARP Inhibitors to Treat HER2+ Breast Cancer |
Erica Stringer-Reasor, M.D. |
University of Alabama, Birmingham |
AL |
North Central Alabama Affiliate |
CCR Clinical |
Improving How We Predict and Prevent Severe Fatigue in Breast Cancer Survivors |
Ines Vaz-Luis, M.D. |
The Institute Gustave Roussy |
France |
N/A |
CCR Clinical |
Improving Immunotherapy for TNBC |
Benjamin Vincent, M.D. |
The University of North Carolina, Chapel Hill |
NC |
North Carolina Triangle to the Coast Affiliate |
CCR Clinical |
PTK6 Promotes Metastasis, Chemoresistance and Altered Immuno-Profiles of TNBC |
Hanna Irie, M.D., Ph.D. |
Icahn School of Medicine, Mount Sinai |
NY |
Greater New York City Affiliate |
CCR Competitive Renewal |
Multifunctional Inhibitors of MET/RON Signaling and Cross-Talk with EGFR/HER2 |
James Janetka, Ph.D. |
Washington University, St. Louis |
MO |
Missouri Affiliate |
CCR Competitive Renewal |
The Ability of Splicing Inhibitors to Target BRCA1 Mutant Breast Cancer |
Neil Johnson, Ph.D. |
Fox Chase Cancer Center |
PA |
Philadelphia Affiliate |
CCR Competitive Renewal |
Analysis of Immunomodulatory Gene Rearrangements in Breast Cancer |
Brian Lehmann, Ph.D. |
Vanderbilt University Medical Center |
TN |
Central Tennessee Affiliate |
CCR Competitive Renewal |
Training Program to Reduce Breast Cancer Disparities in Black and Hispanic Women |
Lorna McNeill, Ph.D., MPH |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
Graduate Training in Disparities Research |
UIC Komen Breast Cancer Epidemiology and Disparities Fellowship |
Garth Rauscher, Ph.D. |
University of Illinois |
IL |
Chicago Affiliate |
Graduate Training in Disparities Research |
Interdisciplinary Graduate Training Program in Cancer Disparities |
Susan Steck, Ph.D., MPH |
University of South Carolina |
SC |
South Carolina Affiliate |
Graduate Training in Disparities Research |
Graduate Training Program in Breast Cancer Disparities at UTSPH |
Sally W. Vernon, Ph.D. |
University of Texas Health Sciences Center at Houston |
TX |
Houston Affiliate |
Graduate Training in Disparities Research |
Resource‐Appropriate Implementation Assessment Frameworks and Breast Cancer Control |
Benjamin Anderson, M.D. |
University of Washington |
WA |
Puget Sound Affiliate |
Komen Scholars Grants |
Establishing Novel Therapeutic Approaches for Breast Cancer |
Alan Ashworth, Ph.D. |
University of California, San Francisco |
CA |
San Francisco Bay Area Affiliate |
Komen Scholars Grants |
Novel Strategies to Overcome Resistance to Standard Therapies in Breast Cancer |
Sunil Badve, M.D. |
Indiana University |
IN |
Central Indiana Affiliate |
Komen Scholars Grants |
Targeting Oxidative Stress Vulnerabilities of Breast Cancer Cells |
Joan Brugge, Ph.D. |
Harvard University |
MA |
New England Affiliate |
Komen Scholars Grants |
Prospective Registry of Multiplex Genetic Testing for Cancer Susceptibility |
Susan Domchek, M.D. |
University of Pennsylvania |
PA |
Philadelphia Affiliate |
Komen Scholars Grants |
Somatic Mutation and Recurrence Risk for Early Stage ER+ Breast Cancer |
Matthew Ellis, Ph.D. |
Baylor University |
TX |
East Central Texas Affiliate |
Komen Scholars Grants |
Adjuvant Therapy Discussions - A Focus on Long Term and Late Effects of Treatment |
Patricia Ganz, M.D. |
University of California, Los Angeles |
CA |
Los Angeles County Affiliate |
Komen Scholars Grants |
Exploratory Study of Immune Cells in Breast Cancer |
Judy Garber, M.D., MPH |
Dana-Farber Cancer Institute |
MA |
New England Affiliate |
Komen Scholars Grants |
Novel Devices to Capture Circulating Tumor Cells |
Daniel Hayes, M.D. |
University of Michigan |
MI |
Michigan Affiliate |
Komen Scholars Grants |
MR Imaging Phenotypes of Breast Cancer |
Nola Hylton, Ph.D. |
University of California, San Francisco |
CA |
San Francisco Bay Area Affiliate |
Komen Scholars Grants |
Comprehensive Breast Cancer Risk Assessment, Screening, Education and Prevention |
Tari King, M.D. |
Dana-Farber Cancer Institute |
MA |
New England Affiliate |
Komen Scholars Grants |
Genomic and Transcriptomic Evolution in Breast Cancer Metastasis |
Adrian Lee, Ph.D. |
University of Pittsburgh |
PA |
Pittsburgh Affiliate |
Komen Scholars Grants |
Mechanism by which BRCA1 Elicits a State of Mammary Epithelial Differentiation Control |
David Livingston, M.D. |
Dana-Farber Cancer Institute |
MA |
New England Affiliate |
Komen Scholars Grants |
Preoperative Radiotherapy to Elicit Critical Immune Stimulating Effects |
Elizabeth Mittendorf, M.D., Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
Komen Scholars Grants |
Breast MRI - Biomarker Development |
Elizabeth Morris, M.D. |
Memorial Sloan-Kettering Cancer Center |
NY |
Greater New York City Affiliate |
Komen Scholars Grants |
ER+ Breast Cancer Recurrence through Dependence Receptor Pathway |
Harikrishna Nakshatri, Ph.D. |
Indiana University |
IN |
Central Indiana Affiliate |
Komen Scholars Grants |
Translating Breast Cancer Genomics in the Clinic |
Olufunmilayo Olopade, M.D. |
University of Chicago |
IL |
Chicago Affiliate |
Komen Scholars Grants |
Targeting Spliceosome Mutations for Breast Cancer Therapy |
Ben Ho Park, M.D., Ph.D. |
Johns Hopkins University |
MD |
Maryland Affiliate |
Komen Scholars Grants |
Breast Cancer Cell Sensitivity to Radiotherapy in the Presence of Targeted Therapies |
Lori Pierce, M.D. |
University of Michigan |
MI |
Michigan Affiliate |
Komen Scholars Grants |
Plk2 Function in Mammary Gland Development and Breast Cancer |
Jeffrey Rosen, Ph.D. |
Baylor University |
TX |
East Central Texas Affiliate |
Komen Scholars Grants |
Genomic Predictors of Chemotherapy‐Induced Toxicity |
Bryan Schneider, M.D. |
Indiana University |
IN |
Central Indiana Affiliate |
Komen Scholars Grants |
Mammary Stem Cells and Breast Cancer |
Geoffrey Wahl, Ph.D. |
The Salk Institute for Biological Studies |
CA |
San Diego Affiliate |
Komen Scholars Grants |
Regulation of Metastasis by Mitochondrial DNA |
Danny Welch, Ph.D. |
University of Kansas |
KS |
Greater Kansas City Affiliate |
Komen Scholars Grants |
Johns Hopkins Breast Cancer Program Longitudinal Repository |
Antonio Wolff, M.D. |
Johns Hopkins University |
MD |
Maryland Affiliate |
Komen Scholars Grants |
Targeting Insulin Receptor in Breast Cancer |
Douglas Yee, M.D. |
University of Minnesota, Twin Cities |
MN |
Minnesota Affiliate |
Komen Scholars Grants |
New drugs for metastatic breast cancer |
Suranganie Dharmawardhane, Ph.D. |
University of Puerto Rico |
Puerto Rico |
Puerto Rico Affiliate |
Opportunity Grants |
Susan G. Komen Tissue Bank at the IU Simon Cancer Center-Infrastructure Support |
Anna Storniolo, M.D. |
Indiana University |
IN |
Central Indiana Affiliate |
Opportunity Grants |
Breast Cancer Evolution and Resistance in Response to HER2-Targeted Therapy |
Jennifer Caswell-Jin, M.D. |
Stanford University |
CA |
San Francisco Bay Area Affiliate |
PDF Basic/Translational |
Elucidating Breast Cancer Disseminated Tumor Cell Phenotypes |
Elizabeth Chislock, Ph.D. |
University of Pennsylvania |
PA |
Philadelphia Affiliate |
PDF Basic/Translational |
Immunotherapeutic Targeting of a Therapy Resistant Oncogenic HER2 Isoform |
Erika Crosby, Ph.D. |
Duke University |
NC |
North Carolina Triangle to the Coast Affiliate |
PDF Basic/Translational |
MAPK12 as a Novel Therapeutic Target for Breast Cancer Brain Metastasis |
Jingzhen Ding, Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
PDF Basic/Translational |
Targeting the EPHA2-YAP/TAZ Signaling Axis in Human Breast Cancer |
Deanna Edwards, Ph.D. |
Vanderbilt University Medical Center |
TN |
Central Tennessee Affiliate |
PDF Basic/Translational |
Investigating Chemoresistance in TNBC Using Single Cell Transcriptomics |
Ruli Gao, Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
PDF Basic/Translational |
Identification of Genetic Drivers in HER2-Enriched/HER2 Negative Breast Cancer |
Susana Garcia Recio, Ph.D. |
The University of North Carolina, Chapel Hill |
NC |
North Carolina Triangle to the Coast Affiliate |
PDF Basic/Translational |
Deep Computational Phenotyping of Breast Cancer Risk with Breast Tomosynthesis |
Aimilia Gastounioti, Ph.D. |
University of Pennsylvania |
PA |
Philadelphia Affiliate |
PDF Basic/Translational |
The Role of Histone H3 Variants in Breast Cancer Metastasis |
Ana Gomes, Ph.D. |
Cornell University |
NY |
Upstate New York Affiliate |
PDF Basic/Translational |
Immunological Determinants of Breast Carcinogenesis in High-Risk Patients |
Joshua Gruber, M.D., Ph.D. |
Stanford University |
CA |
San Francisco Bay Area Affiliate |
PDF Basic/Translational |
PTK6 Inhibition Enhances Chemotherapy Sensitivity and Immune Response in TNBC |
Koichi Ito, Ph.D. |
Icahn School of Medicine, Mount Sinai |
NY |
Greater New York City Affiliate |
PDF Basic/Translational |
Epigenetic Changes Promote Metastasis of TNBC |
Eui-Jun Kim, Ph.D. |
University of Wisconsin, Madison |
WI |
Wisconsin Affiliate |
PDF Basic/Translational |
MCL1 and Chemotherapy Resistance in TNBC |
Kyung-min Lee, Ph.D. |
Vanderbilt University Medical Center |
TN |
Central Tennessee Affiliate |
PDF Basic/Translational |
Contributions of the Mutant BRCA1 Microenvironment to Breast Cancer Development |
Carman Man-Chung Li, Ph.D. |
Harvard University |
MA |
New England Affiliate |
PDF Basic/Translational |
Targeting Replication Stress Response Defects in Triple Negative Breast Cancer |
Daniel McGrail, Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
PDF Basic/Translational |
Targeting RNA-Decay Mechanisms for Treating MYC-Driven Breast Cancers |
Jitendra Meena, Ph.D. |
Baylor University |
TX |
East Central Texas Affiliate |
PDF Basic/Translational |
Myoepithelial Cells in DCIS, Patrolling the Border Against Invasive Cancer |
Elizabeth Mitchell, Ph.D. |
Oregon Health & Science University |
OR |
Oregon & SW Washington Affiliate |
PDF Basic/Translational |
Breast Cancer Epidrivers are New Opportunities for Synthetically Lethal Therapies |
Shoghag Panjarian, Ph.D. |
Temple University |
PA |
Philadelphia Affiliate |
PDF Basic/Translational |
Improving Radiotherapy Efficacy in IBC by Targeting the Tumor Microenvironment |
Omar Rahal, Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
PDF Basic/Translational |
Targeting Metadherin to Reduce Breast Cancer Mortality |
Minhong Shen, Ph.D. |
Princeton University |
NJ |
Central and South Jersey Affiliate |
PDF Basic/Translational |
Molecular Approaches to Stop Breast Tumor Evolution and Improve Treatment |
Teneale Stewart, Ph.D. |
University of Minnesota, Twin Cities |
MN |
Minnesota Affiliate |
PDF Basic/Translational |
Targeting Cancer Cell Metabolism to Treat Breast Cancer Brain Metastasis |
Christina Wong, Ph.D. |
Massachusetts General Hospital |
MA |
New England Affiliate |
PDF Basic/Translational |
Short-Term Lifestyle Interventions for Cardio-Protection from Anthracyclines |
Amy Kirkham, Ph.D. |
University of Alberta |
Canada |
N/A |
PDF Clinical |
Blood Biopsy to Detect Mechanisms of Resistance in HER2+ Metastatic Breast Cancer |
Heather Parsons, M.D. |
Dana-Farber Cancer Institute |
MA |
New England Affiliate |
PDF Clinical |
Discovery of Mechanisms of Resistance of Antiestrogen Therapy in ER+ Breast Cancer |
Carlos Arteaga, M.D. |
Vanderbilt University Medical Center |
TN |
Central Tennessee Affiliate |
Scientific Advisory Board Grants |
Identifying Novel Synthetic Lethal Vulnerabilities to Overcome Endocrine Resistance in Breast Cancer |
Myles Brown, M.D. |
Dana-Farber Cancer Institute |
MA |
New England Affiliate |
Scientific Advisory Board Grants |
Targeting the MELK Protein for the Treatment of Triple-Negative Breast Cancer |
Powel Brown, M.D., Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
Scientific Advisory Board Grants |
Measuring Circulating Tumor Cells in Vivo for Breast Cancer Metastasis Detection |
George Sledge, M.D. |
Stanford University |
CA |
San Francisco Bay Area Affiliate |
Scientific Advisory Board Grants |
2016 Annual Conference on Clinical Cancer Research |
Jeff Allen, Ph.D. |
Friends of Cancer Research |
DC |
N/A |
Sponsored Programs and Partnerships |
2017 Accelerating Anticancer Agent Development and Validation Workshop |
H. Kim Lyerly, M.D. |
Duke University |
NC |
North Carolina Triangle to the Coast Affiliate |
Sponsored Programs and Partnerships |
Advanced Breast Cancer Fourth International Consensus Conference (ABC4) |
Chatrina Melcher |
European School Of Oncology |
Italy |
Susan G. Komen Italia |
Sponsored Programs and Partnerships |
Roundtable on Quality Care for People with Serious Illness |
Sharyl Nass, Ph.D. |
The National Academies of Sciences |
DC |
N/A |
Sponsored Programs and Partnerships |
9th International Symposium on the Breast |
Heather Ortner |
Susan Love Foundation |
CA |
Los Angeles County Affiliate |
Sponsored Programs and Partnerships |
Tenth AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved |
Michael Stewart |
American Association For Cancer Research (AACR) |
PA |
Philadelphia Affiliate |
Sponsored Programs and Partnerships |
AACR: The Science of Cancer Health Disparities Conference |
Michael Stewart |
American Association For Cancer Research (AACR) |
PA |
Philadelphia Affiliate |
Sponsored Programs and Partnerships |
AACR: 2016 San Antonio Breast Cancer Symposium (SABCS) |
Michael Stewart |
American Association For Cancer Research (AACR) |
PA |
Philadelphia Affiliate |
Sponsored Programs and Partnerships |
70th Annual Cancer Symposium (SSO 2017) |
Eileen Widmer |
Society of Surgical Oncology (SSO) |
IL |
Chicago Affiliate |
Sponsored Programs and Partnerships |
Preclinical testing of matriptase as a novel target in inflammatory breast cancer |
Karin List, Ph.D. |
Wayne State University |
MI |
Greater Detroit Affiliate |
Inflammatory Breast Cancer Innovator Grants (*Funded in FY17-18) |
Marker Discovery and Validation in a Prospectively Collected IBC Cohort (INFLAME) |
John Martens, Ph.D. |
Erasmus Universitair Medisch Centrum Rotterdam |
Netherlands |
N/A |
Inflammatory Breast Cancer Innovator Grants |
Function of Lymphatic Vessels in Rapid Progression of Inflammatory Breast Cancer |
Mihaela Skobe, Ph.D. |
Icahn School of Medicine, Mount Sinai |
NY |
Greater New York City Affiliate |
Inflammatory Breast Cancer Innovator Grants |
Susan G. Komen® Symposium: Selective Management of DCIS and the Susan G. Komen® Breast Cancer Research Award |
Eileen Widmer |
The Society of Surgical Oncology |
IL |
Chicagoland Area Affiliate |
Sponsored Partnerships and Programs |
2016 Accelerating Anticancer Agent Development and Validation Workshop |
H. Kim Lyerly, M.D. |
Duke University |
NC |
North Carolina Triangle to the Coast Affiliate |
Sponsored Partnerships and Programs |
AACR Annual Meeting 2016 |
Mitch Stoller |
American Association for Cancer Research |
PA |
Philadelphia Affiliate |
Sponsored Partnerships and Programs |
1st International Invasive Lobular Cancer (ILC) Symposium |
Steffi Oesterreich, Ph.D. |
University of Pittsburgh Cancer Institute |
PA |
Pittsburgh Affiliate |
Sponsored Partnerships and Programs |
IABCR/ Early Detection of Lethal Breast Cancers |
Heidi Feiler, Ph.D. |
Oregon Health & Science University |
OR |
Oregon and SW Washington Affiliate |
Sponsored Partnerships and Programs |
Komen Tissue Bank Think Tank |
Anna Maria Stornolio, M.D. |
Komen Tissue Bank |
IN |
Central Indiana Affiliate |
Sponsored Partnerships and Programs |
24th Biennial Congress of the European Association for Cancer Research (EACR24) |
Rachel Warden |
European Association for Cancer Research (EACR) |
United Kingdom |
N/A |
Sponsored Partnerships and Programs |
Obesity Week 2016; Obesity and Cancer Section Events |
Wendy Demark-Wahnefried, Ph.D, R.D. |
The Obesity Society |
AL |
North Central Alabama Affiliate |
Sponsored Partnerships and Programs |
Inclusion of Breast Cancer Patients with Bone-only Metastasis in Clinical Trials Consensus Development Meeting (Think Tank) |
Julie Gralow, M.D. |
University of Washington |
WA |
Puget Sound Affiliate |
Sponsored Partnerships and Programs |