The following research projects were approved by Susan G. Komen's national Board of Directors for funding,and will be funded once the Grant Agreements between Komen and the Grantee institution(s) are fully-executed. There are 8 types (mechanisms) of grants: Career Catalyst Research (CCR), Career Catalyst Research Competitive Renewal (CCR-CR), Global Grants, Komen Scholars Grants (KS), Opportunity Grants (OG), Scientific Advisory Board Grants (SAB), Sponsored Programs and Partnerships (SPP), and Inflammatory Breast Cancer Innovator Grants: Funded in Partnership with the Milburn Foundation and the Inflammatory Breast Cancer Research Foundation (IBC). For more information on the scientific programs and partnerships that are supported by the Komen Research Program, see here.

To view a snapshot or the investigator-submitted abstract for each grant, please click here.

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Project Title Investigators Organization State/ Country Affiliate Mechanism

Breast Tumor MHC-II Expression Guides Breast Cancer Response to Immunotherapy

Justin Balko, Ph.D., Pharm.D.

Vanderbilt University Medical Center

TN

Central Tennessee Affiliate

CCR Competitive Renewal

Why Do Older Women with Breast Cancer Do Worse?: A Longitudinal Cohort Study

Rachel Ann Freedman, M.D.

Dana-Farber Cancer Institute

MA

New England Affiliate

CCR Competitive Renewal

Targeting Cell Metabolism to Circumvent Chemotherapy Resistance in TNBC

Kristin Brown, Ph.D.

The University of Melbourne

Australia

N/A

CCR Drug Resistance

Targeting the Unfolded Protein Response Pathway to Prevent Therapeutic Resistance

Katherine Cook, Ph.D.

Wake Forest University Health Sciences

NC

N/A

CCR Drug Resistance

Targeting Metabolic Adaptations to Inhibit Breast Tumor Recurrence and Metastasis

Subhamoy Dasgupta, Ph.D.

Roswell Park Alliance Foundation

NY

Upstate New York Affiliate

CCR Drug Resistance

Notch-Driven Epigenetic Program of Triple Negative Breast Cancer

Robert Faryabi, Ph.D.

University of Pennsylvania

PA

Philadelphia Affiliate

CCR Drug Resistance

Immunologic Mechanisms of Resistance to CDK4/6 Inhibition in Breast Cancer

Shom Goel, Ph.D.

Dana-Farber Cancer Institute

MA

New England Affiliate

CCR Drug Resistance

Harnessing Macrophages in Advanced Breast Cancer to Combat Drug Resistance

Jennifer Guerriero, Ph.D.

Dana-Farber Cancer Institute

MA

New England Affiliate

CCR Drug Resistance

Mismatch Repair Defects and Endocrine Therapy Resistance in ER+ breast cancer

Svasti Haricharan, Ph.D.

Sanford Burnham Prebys Medical Discovery Institute

CA

San Diego Affiliate

CCR Drug Resistance

Mechanisms of Stroma-Mediated Drug Resistance in ER+ Breast Cancers

Taru Muranen, Ph.D.

Beth Israel Deaconess Medical Center

MA

New England Affiliate

CCR Drug Resistance

BET Inhibition as a Therapeutic Strategy for ER+ Invasive Lobular Breast Cancer

Darran O'Connor, Ph.D.

Royal College of Surgeons in Ireland

Ireland

N/A

CCR Drug Resistance

Targeting Anthracycline Resistance as a Novel Strategy to Treat TNBC

Amit Tiwari, Ph.D.

University of Toledo Health Science Campus

OH

Northwest Ohio Affiliate

CCR Drug Resistance

Chemo-Sensitization of Triple Negative Breast Cancer by Targeting HuR

Xiaoqing Wu, Ph.D.

The University of Kansas Center for Research

KS

Greater Kansas City Affiliate

CCR Drug Resistance

Harnessing Regulatory T Cell-Dependent Mechanisms for Brain Metastasis Therapy

Paula Bos, Ph.D.

Virginia Commonwealth University

VA

Central Virginia Affiliate

CCR Metastasis

Targeting cancer cell-ECM interactions to prevent breast cancer metastasis

Jose Javier Bravo-Cordero, Ph.D.

Icahn School of Medicine, Mount Sinai

NY

Greater New York City Affiliate

CCR Metastasis

Can eradicated tumor cell clusters prevent metastasis? A preclinical study

Kevin Cheung, M.D.

Fred Hutchinson Cancer Research Center

WA

Puget Sound Affiliate

CCR Metastasis

Targeting Prometastatic Neutrophils to Inhibit Breast Cancer Metastasis

Xia Liu, Ph.D.

Northwestern University Feinberg School of Medicine

IL

Chicago Affiliate

CCR Metastasis

Single Cell Study of Unique Leukocyte Subset Containing Metastatic Tumor Vesicles

Xin Lu, Ph.D.

University of Notre Dame

IN

N/A

CCR Metastasis

Impact of obesity-associated inflammation on breast cancer metastasis

Daniela Quail, Ph.D.

McGill University

Canada

N/A

CCR Metastasis

Wnt pathway regulation of metastatic progression in TNBC

Kevin Roarty, Ph.D.

Baylor College of Medicine

TX

Houston Affiliate

CCR Metastasis

Biomarkers of PARPi Response and Immunogenicity in BRCA-associated MBC

Payal Shah, M.D.

University of Pennsylvania

PA

Philadelphia Affiliate

CCR Metastasis

Intrinsic Epigenomic Regulation of Metastatic Outgrowth in ER-Positive Cancers

Joe Taube, Ph.D.

Baylor University

TX

East Central Texas Affiliate

CCR Metastasis

Identification and Targeting of Clinically Actionable Genes in Bone Metastases

Rebecca Watters, Ph.D.

University of Pittsburgh

PA

Greater Pennsylvania Affiliate

CCR Metastasis

African Breast Cancer - Disparities in Outcomes Postdoctoral Fellow

Valeria McCormack, Ph.D.

International Agency for Research on Cancer

France

N/A

Global Grants

Evidence-Based Sustainable Strategies for Early Diagnosis of Breast Cancer in China

Tsu-Yin Wu, Ph.D.

Eastern Michigan University

MI

Michigan Affiliate

Global Grants

Identification and dissection of breast cancer genetic dependencies

Alan Ashworth, Ph.D.

University of California, San Francisco

CA

San Francisco Bay Area Affiliate

Komen Scholars Grants

Identification of Premalignant Changes in Breast Cancer Cells from BRCA1 Mutant Carriers

Joan Brugge, Ph.D.

Harvard Medical School

MA

New England Affiliate

Komen Scholars Grants

Limiting the inflammation of obesity to prevent breast cancer

Mary Disis, M.D.

University of Washington

WA

Puget Sound Affiliate

Komen Scholars Grants

Liquid Biopsies for Breast Cancer Diagnosis

William Foulkes, MBSS, Ph.D.

The Research Institute of the McGill University Health Centre

Canada

N/A

Komen Scholars Grants

Using Fine Needle Aspirates as a minimally invasive technique for disease monitoring using single cell genomics methods in Triple Negative Breast Cancer (TNBC)

Karen Gelmon, M.D.

Provincial Health Services Authority

Canada

N/A

Komen Scholars Grants

Toxicities of Breast Cancer Treatment

Sharon Giordano, M.D.

University of Texas M.D. Anderson Cancer Center

TX

Houston Affiliate

Komen Scholars Grants

Mechanisms of Resistance to Treatment in Metastatic Breast Cancer

Joe Gray, Ph.D.

Oregon Health & Science University

OR

Oregon and SW Washington Affiliate

Komen Scholars Grants

Novel Devices to Capture Circulating Tumor Cells

Daniel Hayes, M.D.

University of Michigan

MI

Michigan Affiliate

Komen Scholars Grants

PARP Inhibition and Radiotherapy for Patients with Inflammatory Breast Cancer

Reshma Jagsi, M.D., Ph.D.

University of Michigan

MI

Michigan Affiliate

Komen Scholars Grants

Identification of New Genes for Inherited Breast Cancer by Next Generation Sequencing in High-Risk Families

Mary-Claire King, Ph.D.

University of Washington

WA

Puget Sound Affiliate

Komen Scholars Grants

Molecular Imaging of Breast Cancer Metabolism to Predict In Vivo Cancer Behavior

David Mankoff, M.D., Ph.D.

University of Pennsylvania

PA

Philadelphia Affiliate

Komen Scholars Grants

Large Scale Profiling of Triple-Negative Breast Cancer and Implications for Clinical Outcome

Ingrid Mayer, M.D.

Vanderbilt University Medical Center

TN

Central Tennessee Affiliate

Komen Scholars Grants

Targeting the GRHL2/AGR2/LYPD3 Axis in Breast Cancer

Donald McDonnell, Ph.D.

Duke University

NC

North Carolina Triangle to the Coast Affiliate

Komen Scholars Grants

iMETX (Individualized Metabolic RX): A Pilot Study of an Environmental Intervention to Increase Energy Expenditure Among Breast Cancer Survivors

Kathy Miller, M.D.

Indiana University

IN

Central Indiana Affiliate

Komen Scholars Grants

Combinatorial Adaptive Resistance Therapy In Breast Cancer

Gordon Mills, M.D., Ph.D.

University of Texas M.D. Anderson Cancer Center

TX

Houston Affiliate

Komen Scholars Grants

Family History, Genetics, and Environment: Breast Cancer Risk in U.S. Black Women

Julie Palmer, Sc.D.

Trustees of Boston University, B U Medical Campus

MA

New England Affiliate

Komen Scholars Grants

Breast Cancer In Young Women

Ann Partridge, M.D.

Dana-Farber Cancer Institute

MA

New England Affiliate

Komen Scholars Grants

Improving Adherence to Endocrine Hormonal Therapy among Breast Cancer Patients

Amelie Ramirez, Dr.PH

University of Texas Health Science Center at San Antonio

TX

San Antonio Affiliate

Komen Scholars Grants

Exploiting New Patterns of Genome Damage in Triple Negative Breast Cancer

Sohrab Shah, Ph.D.

Memorial Sloan Kettering Cancer Center

NY

Greater New York City Affiliate

Komen Scholars Grants

Optimizing therapy of triple-negative breast cancer

Melinda Telli, M.D.

Stanford University

CA

San Francisco Bay Area Affiliate

Komen Scholars Grants

Regulation Of Metastasis By Mitochondrial DNA

Danny Welch, Ph.D.

University of Kansas Medical Center Research Institute

KS

Greater Kansas City Affiliate

Komen Scholars Grants

Involving Family to Improve Communication in Breast Cancer Care (Sharing in Care)

Antonio Wolff, M.D.

Johns Hopkins University School of Medicine

MD

Maryland Affiliate

Komen Scholars Grants

Predicting Disease Progression from Imaging Data

Regina Barzilay, Ph.D.

Massachusetts Institute of Technology

MA

New England Affiliate

Opportunity Grants

Managing Treatment Burden and Capacity in Breast Cancer Patients

Alex Cheng, Ph.D.

Vanderbilt University Medical Center

TN

Central Tennessee Affiliate

Opportunity Grants

Carolina Breast Cancer Study 3

H. Earp, M.D.

The University of North Carolina, Chapel Hill

NC

North Carolina Triangle to the Coast Affiliate

Opportunity Grants

ASSESS: A Novel Breast Cancer Decision Support Tool

Sharon Giordano, M.D.

The University of Texas MD Anderson Cancer Center

TX

Houston Affiliate

Opportunity Grants

Susan G. Komen Tissue Bank at the IU Simon Cancer Center

Anna Storniolo, M.D.

Indiana University

IN

Central Indiana Affiliate

Opportunity Grants

Profiling Breast Cancer After Pre-Surgical Therapy: A Platform for Discovery of Mechanisms of Drug Resistance

Carlos Arteaga, M.D.

UT Southwestern Medical Center

TX

Dallas County Affiliate

Scientific Advisory Board Grants

Optimizing HER2-targeting Using RNA and DNA-based Predictive Algorithms

Lisa Carey, M.D.

The University of North Carolina, Chapel Hill

NC

North Carolina Triangle to the Coast Affiliate

Scientific Advisory Board Grants

Triple Negative Breast Cancer: Subtypes, Molecular Targets, And Therapeutic Approaches

Jennifer Pietenpol, Ph.D.

Vanderbilt University Medical Center

TN

Central Tennessee Affiliate

Scientific Advisory Board Grants

Scientific and Patient Advocate Sessions

Yibin Kang, Ph.D.

Metastasis Research Society

FL

N/A

Sponsored Programs and Partnerships

2018 Duke-Susan G. Komen Fundamentals and Accelerating Anticancer Agent Development and Validation (AAADV) Workshop

H. Kim Lyerly, M.D.

Duke University

NC

North Carolina Triangle to the Coast Affiliate

Sponsored Programs and Partnerships

AACR

Michael Stewart

American Association for Cancer Research

PA

Philadelphia Affiliate

Sponsored Programs and Partnerships

Susan G. Komen Breast Cancer Challenge at Obesity Week 2017

Laura Tester Meyer

The Obesity Society

MD

Susan G. Komen Washington, D.C. Race for the Cure

Sponsored Programs and Partnerships

The Translational Breast Cancer Research Consortium

Antonio Wolff, M.D.

Johns Hopkins University School of Medicine

MD

Maryland Affiliate

Sponsored Programs and Partnerships

Inflammatory Breast Cancer Innovator Grants: Funded in partnership with the Milburn Foundation and the Inflammatory Breast Cancer Research Foundation*

Preclinical testing of matriptase as a novel target in inflammatory breast cancer

Karin List, Ph.D.

Wayne State University

MI

Greater Detroit Affiliate

Inflammatory Breast Cancer Innovator Grants (*Funded in FY17-18)