The following research projects were approved by Susan G. Komen's national Board of Directors for funding,and will be funded once the Grant Agreements between Komen and the Grantee institution(s) are fully-executed. There are 8 types (mechanisms) of grants: Career Catalyst Research (CCR), Career Catalyst Research Competitive Renewal (CCR-CR), Global Grants, Komen Scholars Grants (KS), Opportunity Grants (OG), Scientific Advisory Board Grants (SAB), Sponsored Programs and Partnerships (SPP), and Inflammatory Breast Cancer Innovator Grants: Funded in Partnership with the Milburn Foundation and the Inflammatory Breast Cancer Research Foundation (IBC). For more information on the scientific programs and partnerships that are supported by the Komen Research Program, see here.
To view a snapshot or the investigator-submitted abstract for each grant, please click here.
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Project Title | Investigators | Organization | State/ Country | Affiliate | Mechanism |
---|---|---|---|---|---|
Breast Tumor MHC-II Expression Guides Breast Cancer Response to Immunotherapy |
Justin Balko, Ph.D., Pharm.D. |
Vanderbilt University Medical Center |
TN |
Central Tennessee Affiliate |
CCR Competitive Renewal |
Why Do Older Women with Breast Cancer Do Worse?: A Longitudinal Cohort Study |
Rachel Ann Freedman, M.D. |
Dana-Farber Cancer Institute |
MA |
New England Affiliate |
CCR Competitive Renewal |
Targeting Cell Metabolism to Circumvent Chemotherapy Resistance in TNBC |
Kristin Brown, Ph.D. |
The University of Melbourne |
Australia |
N/A |
CCR Drug Resistance |
Targeting the Unfolded Protein Response Pathway to Prevent Therapeutic Resistance |
Katherine Cook, Ph.D. |
Wake Forest University Health Sciences |
NC |
N/A |
CCR Drug Resistance |
Targeting Metabolic Adaptations to Inhibit Breast Tumor Recurrence and Metastasis |
Subhamoy Dasgupta, Ph.D. |
Roswell Park Alliance Foundation |
NY |
Upstate New York Affiliate |
CCR Drug Resistance |
Notch-Driven Epigenetic Program of Triple Negative Breast Cancer |
Robert Faryabi, Ph.D. |
University of Pennsylvania |
PA |
Philadelphia Affiliate |
CCR Drug Resistance |
Immunologic Mechanisms of Resistance to CDK4/6 Inhibition in Breast Cancer |
Shom Goel, Ph.D. |
Dana-Farber Cancer Institute |
MA |
New England Affiliate |
CCR Drug Resistance |
Harnessing Macrophages in Advanced Breast Cancer to Combat Drug Resistance |
Jennifer Guerriero, Ph.D. |
Dana-Farber Cancer Institute |
MA |
New England Affiliate |
CCR Drug Resistance |
Mismatch Repair Defects and Endocrine Therapy Resistance in ER+ breast cancer |
Svasti Haricharan, Ph.D. |
Sanford Burnham Prebys Medical Discovery Institute |
CA |
San Diego Affiliate |
CCR Drug Resistance |
Mechanisms of Stroma-Mediated Drug Resistance in ER+ Breast Cancers |
Taru Muranen, Ph.D. |
Beth Israel Deaconess Medical Center |
MA |
New England Affiliate |
CCR Drug Resistance |
BET Inhibition as a Therapeutic Strategy for ER+ Invasive Lobular Breast Cancer |
Darran O'Connor, Ph.D. |
Royal College of Surgeons in Ireland |
Ireland |
N/A |
CCR Drug Resistance |
Targeting Anthracycline Resistance as a Novel Strategy to Treat TNBC |
Amit Tiwari, Ph.D. |
University of Toledo Health Science Campus |
OH |
Northwest Ohio Affiliate |
CCR Drug Resistance |
Chemo-Sensitization of Triple Negative Breast Cancer by Targeting HuR |
Xiaoqing Wu, Ph.D. |
The University of Kansas Center for Research |
KS |
Greater Kansas City Affiliate |
CCR Drug Resistance |
Harnessing Regulatory T Cell-Dependent Mechanisms for Brain Metastasis Therapy |
Paula Bos, Ph.D. |
Virginia Commonwealth University |
VA |
Central Virginia Affiliate |
CCR Metastasis |
Targeting cancer cell-ECM interactions to prevent breast cancer metastasis |
Jose Javier Bravo-Cordero, Ph.D. |
Icahn School of Medicine, Mount Sinai |
NY |
Greater New York City Affiliate |
CCR Metastasis |
Can eradicated tumor cell clusters prevent metastasis? A preclinical study |
Kevin Cheung, M.D. |
Fred Hutchinson Cancer Research Center |
WA |
Puget Sound Affiliate |
CCR Metastasis |
Targeting Prometastatic Neutrophils to Inhibit Breast Cancer Metastasis |
Xia Liu, Ph.D. |
Northwestern University Feinberg School of Medicine |
IL |
Chicago Affiliate |
CCR Metastasis |
Single Cell Study of Unique Leukocyte Subset Containing Metastatic Tumor Vesicles |
Xin Lu, Ph.D. |
University of Notre Dame |
IN |
N/A |
CCR Metastasis |
Impact of obesity-associated inflammation on breast cancer metastasis |
Daniela Quail, Ph.D. |
McGill University |
Canada |
N/A |
CCR Metastasis |
Wnt pathway regulation of metastatic progression in TNBC |
Kevin Roarty, Ph.D. |
Baylor College of Medicine |
TX |
Houston Affiliate |
CCR Metastasis |
Biomarkers of PARPi Response and Immunogenicity in BRCA-associated MBC |
Payal Shah, M.D. |
University of Pennsylvania |
PA |
Philadelphia Affiliate |
CCR Metastasis |
Intrinsic Epigenomic Regulation of Metastatic Outgrowth in ER-Positive Cancers |
Joe Taube, Ph.D. |
Baylor University |
TX |
East Central Texas Affiliate |
CCR Metastasis |
Identification and Targeting of Clinically Actionable Genes in Bone Metastases |
Rebecca Watters, Ph.D. |
University of Pittsburgh |
PA |
Greater Pennsylvania Affiliate |
CCR Metastasis |
African Breast Cancer - Disparities in Outcomes Postdoctoral Fellow |
Valeria McCormack, Ph.D. |
International Agency for Research on Cancer |
France |
N/A |
Global Grants |
Evidence-Based Sustainable Strategies for Early Diagnosis of Breast Cancer in China |
Tsu-Yin Wu, Ph.D. |
Eastern Michigan University |
MI |
Michigan Affiliate |
Global Grants |
Identification and dissection of breast cancer genetic dependencies |
Alan Ashworth, Ph.D. |
University of California, San Francisco |
CA |
San Francisco Bay Area Affiliate |
Komen Scholars Grants |
Identification of Premalignant Changes in Breast Cancer Cells from BRCA1 Mutant Carriers |
Joan Brugge, Ph.D. |
Harvard Medical School |
MA |
New England Affiliate |
Komen Scholars Grants |
Limiting the inflammation of obesity to prevent breast cancer |
Mary Disis, M.D. |
University of Washington |
WA |
Puget Sound Affiliate |
Komen Scholars Grants |
Liquid Biopsies for Breast Cancer Diagnosis |
William Foulkes, MBSS, Ph.D. |
The Research Institute of the McGill University Health Centre |
Canada |
N/A |
Komen Scholars Grants |
Using Fine Needle Aspirates as a minimally invasive technique for disease monitoring using single cell genomics methods in Triple Negative Breast Cancer (TNBC) |
Karen Gelmon, M.D. |
Provincial Health Services Authority |
Canada |
N/A |
Komen Scholars Grants |
Toxicities of Breast Cancer Treatment |
Sharon Giordano, M.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
Komen Scholars Grants |
Mechanisms of Resistance to Treatment in Metastatic Breast Cancer |
Joe Gray, Ph.D. |
Oregon Health & Science University |
OR |
Oregon and SW Washington Affiliate |
Komen Scholars Grants |
Novel Devices to Capture Circulating Tumor Cells |
Daniel Hayes, M.D. |
University of Michigan |
MI |
Michigan Affiliate |
Komen Scholars Grants |
PARP Inhibition and Radiotherapy for Patients with Inflammatory Breast Cancer |
Reshma Jagsi, M.D., Ph.D. |
University of Michigan |
MI |
Michigan Affiliate |
Komen Scholars Grants |
Identification of New Genes for Inherited Breast Cancer by Next Generation Sequencing in High-Risk Families |
Mary-Claire King, Ph.D. |
University of Washington |
WA |
Puget Sound Affiliate |
Komen Scholars Grants |
Molecular Imaging of Breast Cancer Metabolism to Predict In Vivo Cancer Behavior |
David Mankoff, M.D., Ph.D. |
University of Pennsylvania |
PA |
Philadelphia Affiliate |
Komen Scholars Grants |
Large Scale Profiling of Triple-Negative Breast Cancer and Implications for Clinical Outcome |
Ingrid Mayer, M.D. |
Vanderbilt University Medical Center |
TN |
Central Tennessee Affiliate |
Komen Scholars Grants |
Targeting the GRHL2/AGR2/LYPD3 Axis in Breast Cancer |
Donald McDonnell, Ph.D. |
Duke University |
NC |
North Carolina Triangle to the Coast Affiliate |
Komen Scholars Grants |
iMETX (Individualized Metabolic RX): A Pilot Study of an Environmental Intervention to Increase Energy Expenditure Among Breast Cancer Survivors |
Kathy Miller, M.D. |
Indiana University |
IN |
Central Indiana Affiliate |
Komen Scholars Grants |
Combinatorial Adaptive Resistance Therapy In Breast Cancer |
Gordon Mills, M.D., Ph.D. |
University of Texas M.D. Anderson Cancer Center |
TX |
Houston Affiliate |
Komen Scholars Grants |
Family History, Genetics, and Environment: Breast Cancer Risk in U.S. Black Women |
Julie Palmer, Sc.D. |
Trustees of Boston University, B U Medical Campus |
MA |
New England Affiliate |
Komen Scholars Grants |
Breast Cancer In Young Women |
Ann Partridge, M.D. |
Dana-Farber Cancer Institute |
MA |
New England Affiliate |
Komen Scholars Grants |
Improving Adherence to Endocrine Hormonal Therapy among Breast Cancer Patients |
Amelie Ramirez, Dr.PH |
University of Texas Health Science Center at San Antonio |
TX |
San Antonio Affiliate |
Komen Scholars Grants |
Exploiting New Patterns of Genome Damage in Triple Negative Breast Cancer |
Sohrab Shah, Ph.D. |
Memorial Sloan Kettering Cancer Center |
NY |
Greater New York City Affiliate |
Komen Scholars Grants |
Optimizing therapy of triple-negative breast cancer |
Melinda Telli, M.D. |
Stanford University |
CA |
San Francisco Bay Area Affiliate |
Komen Scholars Grants |
Regulation Of Metastasis By Mitochondrial DNA |
Danny Welch, Ph.D. |
University of Kansas Medical Center Research Institute |
KS |
Greater Kansas City Affiliate |
Komen Scholars Grants |
Involving Family to Improve Communication in Breast Cancer Care (Sharing in Care) |
Antonio Wolff, M.D. |
Johns Hopkins University School of Medicine |
MD |
Maryland Affiliate |
Komen Scholars Grants |
Predicting Disease Progression from Imaging Data |
Regina Barzilay, Ph.D. |
Massachusetts Institute of Technology |
MA |
New England Affiliate |
Opportunity Grants |
Managing Treatment Burden and Capacity in Breast Cancer Patients |
Alex Cheng, Ph.D. |
Vanderbilt University Medical Center |
TN |
Central Tennessee Affiliate |
Opportunity Grants |
Carolina Breast Cancer Study 3 |
H. Earp, M.D. |
The University of North Carolina, Chapel Hill |
NC |
North Carolina Triangle to the Coast Affiliate |
Opportunity Grants |
ASSESS: A Novel Breast Cancer Decision Support Tool |
Sharon Giordano, M.D. |
The University of Texas MD Anderson Cancer Center |
TX |
Houston Affiliate |
Opportunity Grants |
Susan G. Komen Tissue Bank at the IU Simon Cancer Center |
Anna Storniolo, M.D. |
Indiana University |
IN |
Central Indiana Affiliate |
Opportunity Grants |
Profiling Breast Cancer After Pre-Surgical Therapy: A Platform for Discovery of Mechanisms of Drug Resistance |
Carlos Arteaga, M.D. |
UT Southwestern Medical Center |
TX |
Dallas County Affiliate |
Scientific Advisory Board Grants |
Optimizing HER2-targeting Using RNA and DNA-based Predictive Algorithms |
Lisa Carey, M.D. |
The University of North Carolina, Chapel Hill |
NC |
North Carolina Triangle to the Coast Affiliate |
Scientific Advisory Board Grants |
Triple Negative Breast Cancer: Subtypes, Molecular Targets, And Therapeutic Approaches |
Jennifer Pietenpol, Ph.D. |
Vanderbilt University Medical Center |
TN |
Central Tennessee Affiliate |
Scientific Advisory Board Grants |
Scientific and Patient Advocate Sessions |
Yibin Kang, Ph.D. |
Metastasis Research Society |
FL |
N/A |
Sponsored Programs and Partnerships |
2018 Duke-Susan G. Komen Fundamentals and Accelerating Anticancer Agent Development and Validation (AAADV) Workshop |
H. Kim Lyerly, M.D. |
Duke University |
NC |
North Carolina Triangle to the Coast Affiliate |
Sponsored Programs and Partnerships |
AACR |
Michael Stewart |
American Association for Cancer Research |
PA |
Philadelphia Affiliate |
Sponsored Programs and Partnerships |
Susan G. Komen Breast Cancer Challenge at Obesity Week 2017 |
Laura Tester Meyer |
The Obesity Society |
MD |
Susan G. Komen Washington, D.C. Race for the Cure |
Sponsored Programs and Partnerships |
The Translational Breast Cancer Research Consortium |
Antonio Wolff, M.D. |
Johns Hopkins University School of Medicine |
MD |
Maryland Affiliate |
Sponsored Programs and Partnerships |
Inflammatory Breast Cancer Innovator Grants: Funded in partnership with the Milburn Foundation and the Inflammatory Breast Cancer Research Foundation* |
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Preclinical testing of matriptase as a novel target in inflammatory breast cancer |
Karin List, Ph.D. |
Wayne State University |
MI |
Greater Detroit Affiliate |
Inflammatory Breast Cancer Innovator Grants (*Funded in FY17-18) |