The following research projects were approved for funding, and will be funded once the Grant Agreements between Komen and the Grantee institution(s) are fully-executed. There are 5 types (mechanisms) of grants: ASPIRE: A Supplement to Promote Inclusion for Research Excellence, Career Catalyst Research Grants, Scientific Partnerships and Programs Grants, Leadership Grants, and Opportunity Grants.

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Project Title Investigators Organization State/ Country Mechanism

Targeting Antigen Presentation to Improve Immunotherapy Response

Balko, Justin

Vanderbilt University Medical Center

TN

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Targeting Metabolism to Enhance Immunotherapy in Advanced Breast Cancer

Guerriero, Jennifer

Brigham and Women's Hospital

MA

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Neighborhood Disadvantage, Tumor Characteristics, and Breast Cancer Survival in U.S. Black Women

Palmer, Julie

Boston University

MA

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Targeting ZFP296 to Prevent Reactivation of Dormant Metastatic Breast Cancer Cells

Sosa, Maria

Albert Einstein College of Medicine

NY

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Effects of Chronic Social Stress on Mammary Gland Development and Cancer Risk

Brady, Matthew

The University of Chicago

IL

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Mechanical Regulation of Estrogen Signaling in Breast Cancer Bone Metastasis

Rhoades, Julie

Vanderbilt University Medical Center

TN

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Alcohol as a Dietary Factor for Breast Cancer

Schug, Zachary

University of Pennsylvania

PA

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Constitutively Active SUMO Modified Androgen Receptors in HR+ Breast Cancer

Bawa-Khalfe, Tasneem

University of Houston

TX

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Evaluation of Steroidal Natural Compounds for the Treatment of Inflammatory Breast Cancer

Martinez-Montemayor, Michelle

Universidad Central del Caribe

PR

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Progesterone Promotes an Immune Privileged Microenvironment in Breast Cancer

Hagan, Christy

University of Kansas Medical Center

KS

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Oxygen Tension - Dependent Changes in Breast Cancer and Drug Sensitivity

Nakshatri, Harikrishna

Indiana University

IN

ASPIRE: A Supplement to Promote Inclusion for Research Excellence

Eliminating Metastasis Potential by Promoting Breast Cancer Dormancy via Macrophages

Borriello, Lucia

Temple University

PA

Career Catalyst Research

Closing the Gap: Mixed Methods Approaches to Reducing Breast Cancer Disparities

Narayan, Anand

University of Wisconsin-Madison

WI

Career Catalyst Research

Holistic Decision-Making Framework for Personalized Breast Cancer Screening

Barufaldi, Bruno

University of Pennsylvania

PA

Career Catalyst Research

Using Natural Killer Cells to Treat Metastatic Breast Cancer

Chan, Isaac

University of Texas Southwestern Medical Center

TX

Career Catalyst Research

Deep Learning Mammographic Evaluations to Refine Breast Cancer Risk

McGuinness, Julia

Columbia University

NY

Career Catalyst Research

Novel Therapy to Inhibit DNA Repair Mechanisms and Prevent Tumor Cell Division in Ethnically Diverse Breast Cancer

Merrill, Nathan

University of Michigan

MI

Career Catalyst Research

Using AI-Based Methods on Medical Imaging to Predict Breast Cancer Risk in Black Women

Gastounioti, Aimilia

Washington University in St. Louis

MO

Career Catalyst Research

The Paradox of Obesity, Tumor Progression, and Checkpoint Inhibition in TNBC

Crosby, Erika

Duke University

NC

Career Catalyst Research

Examining Immune Mechanisms of Margetuximab vs Trastuzumab in HER2+ Breast Cancer

Waks, Adrienne

Dana-Farber Cancer Institute

MA

Career Catalyst Research

Targeting Dysfunctional DNA Replication Origin Control in Breast Cancer

Hill, Sarah

Dana-Farber Cancer Institute

MA

Career Catalyst Research

Targeting GPR84 to Overcome Resistance to Immunotherapy

Xin, Gang

The Ohio State University

OH

Career Catalyst Research

A New Chromatin-Directed Vulnerability in BRCA-Mutant Breast Cancers

Verma, Priyanka

Washington University in St. Louis

MO

Career Catalyst Research

Biomarkers of Racially Disparate Drug Response in Triple Negative Breast Cancer

Kabraji, Sheheryar

Dana-Farber Cancer Institute

MA

Career Catalyst Research

Navigator-Assisted Hypofractionation (NAVAH) Short-Course Radiation Therapy in Black Breast Cancer Patients

McClelland, Shearwood

University Hospitals Cleveland Medical Center

OH

Career Catalyst Research

The Translational Breast Cancer Research Consortium

Wolff, Antonio

Johns Hopkins University School of Medicine

TX

Opportunity Grants

Carolina Breast Cancer Study 4

Troester, Melissa

The University of North Carolina at Chapel Hill

NC

Opportunity Grants

Capturing Patient Reported Data to Impact Disparities in Metastatic Breast Cancer

Reeder-Hayes, Katherine and Check, Devon

The University of North Carolina at Chapel Hill

NC

Opportunity Grants

ShareForCures Biorepository Partner

Cote, Michele

Indiana University

IN

Opportunity Grants

Discovering Novel Immunotherapy Strategies to Treat BRCA-mutated Breast Cancer

Ashworth, Alan

The University of California San Francisco

CA

Leadership Grants

Understanding Antibody-Drug Conjugate (ADC) Sensitivity and Resistance in Breast Cancer

Carey, Lisa

The University of North Carolina at Chapel Hill

NC

Leadership Grants

Breast Cancer in Young Women: Improving Understanding to Optimize Outcomes

Partridge, Ann

Dana-Farber Cancer Institute

MA

Leadership Grants

Triple Negative Breast Cancer in Women with African Ancestry

Newman, Lisa

Weill Medical College of Cornell University

NY

Leadership Grants

Identification of the Genetic Drivers of HER2-Enriched Subtype Breast Cancers

Perou, Charles

The University of North Carolina at Chapel Hill

NC

Leadership Grants

Targeting Spliceosome Mutations for Breast Cancer Therapy

Park, Ben

Vanderbilt University Medical Center

TN

Leadership Grants

Breast Cancer Treatment Initiation and Completion

Chavez Mac Gregor, Mariana

University of Texas MD Anderson Cancer Center

TX

Leadership Grants

Resistance to CDK4/6 Inhibitors in Estrogen Receptor-Positive Breast Cancer

Arteaga, Carlos L.

University of Texas Southwestern Medical Center

TX

Leadership Grants

Epigenetic and Epitranscriptomic Targets in Breast Cancer

Brown, Myles

Dana-Farber Cancer Institute

MA

Leadership Grants

Molecular Imaging to Measure Breast Cancer Extent and Biology

Mankoff, David

University of Pennsylvania

PA

Leadership Grants

Targeting the LYPD3 Signaling Pathway in Metastatic Breast Cancer

McDonnell, Donald

Duke University

NC

Leadership Grants

Mechanistic Insights into Breast Cancers with Chromosome 8q24.3 Amplification

Nakshatri, Harikrishna

Indiana University

IN

Leadership Grants

Translating Breast Cancer Genomics in the Clinic

Olopade, Olufunmilayo

The University of Chicago

IL

Leadership Grants

Treatment of Breast Cancer Metastasis by Therapeutic Manipulation of Macrophages

Rosen, Jeffrey

Baylor College of Medicine

TX

Leadership Grants

Optimizing Treatment of Early Stage Triple Negative Breast Cancer

Wolff, Antonio

Johns Hopkins University School of Medicine

MD

Leadership Grants

Intervention to Reduce Food Insecurity in Patients with Metastatic Breast Cancer

Hershman, Dawn

Columbia University

NY

Leadership Grants

Exploiting Unique Biology for Therapeutic Benefit in Black Patients with Breast Cancer

Miller, Kathy

Indiana University

IN

Leadership Grants

Use of PRS and Early Detection Assays for Decision Making Regarding Risk Management in BRCA Carriers

Domchek, Susan

University of Pennsylvania

PA

Leadership Grants

Translational Approach to Mitigating Racial Disparities in Drug-Induced Toxicity

Schneider, Bryan

Indiana University

IN

Leadership Grants

Advanced Breast Cancer Seventh International Consensus Conference (ABC7)

Ventura,Roberta

Associação Advanced Breast Cancer Global Alliance

Portugal

Scientific Partnerships and Programs Grants